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Next generation sequencing in cancer research. / Volume 1, Decoding the cancer genome

Author: Wei Wu; Hani Choudhry
Publisher: New York, NY : Springer, 2013.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Next Generation Sequencing (NGS) technology has placed important milestones in the life science and changed the direction in biomedical science inclucing cancer. Scientists around the world are attempting to find the root cause of cancer and they are looking for more direct and effective means to cure cancer. This journey to conquer cancer is more optimistic now with the unfolding of the cancer genome. This book  Read more...
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Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Wei Wu; Hani Choudhry
ISBN: 9781461476450 1461476453
OCLC Number: 869587553
Notes: Titre de l'écran-titre (visionné le 30 septembre 2013).
Description: 1 online resource (1 texte électronique (xxiii, 383 pages)) illustrations, fichiers PDF.
Contents: Introduction: next generation sequencing technology and cancer research --
The majority of total nuclear-encoded non-ribosomal RNA in a human cell is dark matter unannotated RNA --
Total RNA-seq of breast cancer in hypoxia --
Altered antisense-to-sense transcript ratios in breast cancer --
Identification of piRNAs in Hela cells by massive parallel sequencing --
Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia --
Whole-Exome Sequencing Identifies FAM20A Mutations as a Cause of Amelogenesis Imperfecta and Gingival Hyperplasia Syndrome --
Whole-exome sequencing in CIC and IDH1/2 contributing to human oligodendroglioma --
Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing --
Tumour evolution inferred by single-cell sequencing --
Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq --
Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNASeq analysis --
Whole genome DNA methylation analysis based on high throughput sequencing technology --
Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors --
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq --
MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action --
Genome-wide identification of polycomb-associated RNAs by RIP-seq --
Single-molecule sequencing: sequence methods to enable accurate quantisation --
Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells --
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA --
The genome information process for cancer research: the challenge and perspective.
Other Titles: Decoding the cancer genome
Responsibility: Wei Wu, Hani Choudhry, Editors.
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