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Nimesulide--actions and uses

Author: K D Rainsford
Publisher: Basel ; Boston : Birkhäuser, ©2005.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Nimesulide--actions and uses.
Basel ; Boston : Birkhäuser, ©2005
(DLC) 2005048130
(OCoLC)60373352
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: K D Rainsford
ISBN: 9783764374105 3764374101 3764370688 9783764370688
OCLC Number: 262681489
Description: 1 online resource (xvi, 433 pages) : illustrations (some color)
Contents: The discovery, development and novel actions of nimesulide --
Pharmacokinetics of nimesulide --
Pharmaceutical formulations of nimesulide --
Pharmacological properties of nimesulide --
Clinical applications of nimesulide in pain, arthritic conditions and fever --
Adverse reactions and their mechanisms from nimesulide.
Responsibility: edited by K.D. Rainsford.
More information:

Abstract:

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs. The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.

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