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Nitric oxide

Author: J -L Balligand; B Mayer
Publisher: Berlin ; New York : Springer, ©2000.
Series: Handbook of experimental pharmacology, v. 143.
Edition/Format:   Print book : EnglishView all editions and formats
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Document Type: Book
All Authors / Contributors: J -L Balligand; B Mayer
ISBN: 3540661220 9783540661221
OCLC Number: 43083311
Description: xxix, 667 pages : illustrations ; 24 cm.
Contents: Introduction --
Sect. 1. Chemistry --
The chemical biology of nitric oxide, balancing nitric oxide with oxidative and nitrosative stress --
Sect. 2. Biochemistry and pharmacology of NO synthesis and action --
Enzymology of nitric oxide synthases --
Regulation of nitric oxide synthase expression and activity --
Enzymology of soluble guanylyl cyclase --
Nitric oxide synthase inhibitors I: substrate analogs and heme ligands --
Nitric-oxide-synthase inhibitors II --
pterin antagonists/anti-pterins --
Mechanisms of cellular resistance against nitric oxide --
Sect. 3. Physiological functions of NO --
Nitric oxide and regulation of vascular tone --
Regulation of cardiac function by nitric oxide --
Regulation of platelet function --
The physiological roles of nitric oxide in the central nervous system --
The role of nitric oxide in the peripheral nervous system --
Nitric oxide and neuroendocrine function --
The role of nitric oxide in kidney function --
Sect. 4. The role of pharmacological action of NO in human disease --
Therapeutic importance of nitrovasodilators --
Therapeutic potential of NOS inhibitors in septic shock --
Inhalation therapy with nitric oxide gas --
The function of nitric oxide in the immune system --
Nitric oxide: a true inflammatory mediator --
Nitric oxide in the immunopathogenesis of type 1 diabetes --
The role of nitric oxide in cardiac ischaemia --
reperfusion --
Nitric oxide and atherosclerosis --
Nitric oxide in brain ischemia/reperfusion injury --
Therapeutic potential of nitric oxide synthase gene manipulation.
Series Title: Handbook of experimental pharmacology, v. 143.
Responsibility: contributors, J.-L. Balligand [and others] ; editor, B. Mayer.

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