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NK cell signaling to cytotoxicity : part 1

Author: Dan Billadeau
Publisher: London : Henry Stewart Talks, 2010.
Series: Henry Stewart talks., Biomedical & life sciences collection., Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer.
Edition/Format:   eVideo : Clipart/images/graphics : EnglishView all editions and formats
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Material Type: Clipart/images/graphics, Internet resource, Videorecording
Document Type: Internet Resource, Computer File, Visual material
All Authors / Contributors: Dan Billadeau
OCLC Number: 720056289
Notes: Animated audio-visual presentation with synchronized narration.
Title from title frames.
Description: 1 streaming video file (55 min.) : digital, mono, SWF file, sound, color.
Details: Mode of access: World Wide Web.; System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.
Contents: NK cell cytotoxicity --
Introduction to NK cell activating receptors --
Regulation of NK cell cytotoxicity by immunoreceptor tyrosine-based activation motif associated receptors --
The downstream targets regulating NK cytolytic activity --
PI3K pathway is required for the development of cellular cytotoxicity --
LAT/NTAL are required for DAP12-initiated cytotoxicity and production of interferon gamma --
PLC[gamma]2 is required for NK cell killing --
Vav proteins are linked to NK cell activating receptors and regulate the development of cellular cytotoxicity --
Rho family GTP-binding proteins regulate NK cell-mediated cytotoxicity.
Series Title: Henry Stewart talks., Biomedical & life sciences collection., Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer.
Other Titles: NK cell signaling to cytotoxicity ; part I
Responsibility: Daniel D. Billadeau.
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