skip to content
Non-clinical vascular infusion technology Preview this item
ClosePreview this item
Checking...

Non-clinical vascular infusion technology

Author: Owen P Green; Guy Healing
Publisher: Boca Raton : CRC Press, Taylor & Francis Group, [2014]-
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Preface There are many pharmaceuticals on the market or undergoing clinical trials that require intravenous infusion, for either short or longer periods, intermittently or continuously, and so this book should be of interest to those in pharmaceutical research and development, as well as in other research areas. These applications include chemotherapy and the treatment of various diseases such as HIV, hepatitis C,  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Document Type: Book
All Authors / Contributors: Owen P Green; Guy Healing
ISBN: 9781439874493 1439874492 9781439874455 143987445X 1439874506 9781439874509
OCLC Number: 703208700
Description: volumes : illustrations (some color) ; 24 cm
Contents: Volume 1. The science --
volume 2. The techniques.
Responsibility: Owen P. Green and Guy Healing.

Abstract:

"Preface There are many pharmaceuticals on the market or undergoing clinical trials that require intravenous infusion, for either short or longer periods, intermittently or continuously, and so this book should be of interest to those in pharmaceutical research and development, as well as in other research areas. These applications include chemotherapy and the treatment of various diseases such as HIV, hepatitis C, and cardiovascular disease, as well as during and following problematical surgical procedures. It is a regulatory and ethical requirement that these pharmaceuticals first be tested on both rodents and non-rodents by the clinical route, and so the range of pre-clinical experimental models is covered. The technique of prolonged intravenous delivery in conscious, free-moving animal models has also broadened the opportunities to study and evaluate the safety and efficacy of those products that have limiting biological or chemical properties such as half-life and formulation issues. In 2000 the first book covering pre-clinical infusion techniques was published by Taylor & Francis (Handbook of Pre-Clinical Continuous Intravenous Infusion, Healing and Smith, editors) and this has become the singular reference source for this technology up to the present time. However, it is now recognised that a number of the techniques have been refined since that time, and also that new and improved equipment has been developed"--Provided by publisher.

Reviews

Editorial reviews

Publisher Synopsis

"Good science and good welfare go hand in hand. Innovative science and technology can be used to improve animal welfare. Equally, the 3Rs (replacement, refinement and reduction of animals in Read more...

 
User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/703208700> # Non-clinical vascular infusion technology
    a schema:Book, schema:CreativeWork ;
   library:oclcnum "703208700" ;
   library:placeOfPublication <http://id.loc.gov/vocabulary/countries/flu> ;
   schema:about <http://experiment.worldcat.org/entity/work/data/790268447#Topic/drug_evaluation_preclinical> ; # Drug Evaluation, Preclinical
   schema:about <http://experiment.worldcat.org/entity/work/data/790268447#Topic/infusions_intravenous_methods> ; # Infusions, Intravenous--methods
   schema:about <http://id.worldcat.org/fast/973306> ; # Infusion therapy
   schema:about <http://experiment.worldcat.org/entity/work/data/790268447#Topic/models_animal> ; # Models, Animal
   schema:about <http://dewey.info/class/615.6/e23/> ;
   schema:about <http://id.worldcat.org/fast/898667> ; # Drug delivery systems
   schema:author <http://viaf.org/viaf/305025437> ; # Owen P. Green
   schema:author <http://viaf.org/viaf/84839398> ; # Guy Healing
   schema:bookFormat bgn:PrintBook ;
   schema:datePublished "2014/9999" ;
   schema:description "Volume 1. The science -- volume 2. The techniques."@en ;
   schema:description ""Preface There are many pharmaceuticals on the market or undergoing clinical trials that require intravenous infusion, for either short or longer periods, intermittently or continuously, and so this book should be of interest to those in pharmaceutical research and development, as well as in other research areas. These applications include chemotherapy and the treatment of various diseases such as HIV, hepatitis C, and cardiovascular disease, as well as during and following problematical surgical procedures. It is a regulatory and ethical requirement that these pharmaceuticals first be tested on both rodents and non-rodents by the clinical route, and so the range of pre-clinical experimental models is covered. The technique of prolonged intravenous delivery in conscious, free-moving animal models has also broadened the opportunities to study and evaluate the safety and efficacy of those products that have limiting biological or chemical properties such as half-life and formulation issues. In 2000 the first book covering pre-clinical infusion techniques was published by Taylor & Francis (Handbook of Pre-Clinical Continuous Intravenous Infusion, Healing and Smith, editors) and this has become the singular reference source for this technology up to the present time. However, it is now recognised that a number of the techniques have been refined since that time, and also that new and improved equipment has been developed"--Provided by publisher."@en ;
   schema:exampleOfWork <http://worldcat.org/entity/work/id/790268447> ;
   schema:inLanguage "en" ;
   schema:name "Non-clinical vascular infusion technology"@en ;
   schema:productID "703208700" ;
   schema:workExample <http://worldcat.org/isbn/9781439874509> ;
   schema:workExample <http://worldcat.org/isbn/9781439874455> ;
   schema:workExample <http://worldcat.org/isbn/9781439874493> ;
   wdrs:describedby <http://www.worldcat.org/title/-/oclc/703208700> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/790268447#Topic/drug_evaluation_preclinical> # Drug Evaluation, Preclinical
    a schema:Intangible ;
   schema:name "Drug Evaluation, Preclinical"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/790268447#Topic/infusions_intravenous_methods> # Infusions, Intravenous--methods
    a schema:Intangible ;
   schema:name "Infusions, Intravenous--methods"@en ;
    .

<http://id.worldcat.org/fast/898667> # Drug delivery systems
    a schema:Intangible ;
   schema:name "Drug delivery systems"@en ;
    .

<http://id.worldcat.org/fast/973306> # Infusion therapy
    a schema:Intangible ;
   schema:name "Infusion therapy"@en ;
    .

<http://viaf.org/viaf/305025437> # Owen P. Green
    a schema:Person ;
   schema:familyName "Green" ;
   schema:givenName "Owen P." ;
   schema:name "Owen P. Green" ;
    .

<http://viaf.org/viaf/84839398> # Guy Healing
    a schema:Person ;
   schema:birthDate "1961" ;
   schema:familyName "Healing" ;
   schema:givenName "Guy" ;
   schema:name "Guy Healing" ;
    .

<http://worldcat.org/isbn/9781439874455>
    a schema:ProductModel ;
   schema:isbn "143987445X" ;
   schema:isbn "9781439874455" ;
    .

<http://worldcat.org/isbn/9781439874493>
    a schema:ProductModel ;
   schema:isbn "1439874492" ;
   schema:isbn "9781439874493" ;
    .

<http://worldcat.org/isbn/9781439874509>
    a schema:ProductModel ;
   schema:isbn "1439874506" ;
   schema:isbn "9781439874509" ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.