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NPY family of peptides in neurobiology, cardiovascular and metabolic disorders : from genes to therapeutics

Author: Zofia Zukowska; Giora Z Feuerstein
Publisher: Basel ; Boston : Birkhauser Verlag, ©2006.
Series: EXS, 95.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists which are in clinical development for obesity  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Print version:
NPY family of peptides in neurobiology, cardiovascular and metabolic disorders.
Basel ; Boston : Birkhauser Verlag, ©2006
(DLC) 2005053057
(OCoLC)61309443
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Zofia Zukowska; Giora Z Feuerstein
ISBN: 3764371552 9783764371555 3764374179 9783764374174 9786610608812 6610608814
OCLC Number: 67721961
Description: 1 online resource (ix, 279 pages) : illustrations.
Contents: NPY family of peptides in neurobiology, cardiovascular system and metabolism: genes, diseases and therapeutics.- An overview of neuropeptide Y: pharmacology to molecular biology and receptor localization.- Molecular ligand-receptor interaction of the NPY / PP peptide family.- Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctions.- NPY and NPY receptors: presence, distribution and roles in the regulation of the endocardial endothelium and cardiac function.- Neuropeptide Y and sympathetic control of vascular tone in hypertension.- Neuropeptide Y and the cerebral circulation.- Neuropeptide Y and the heart: implication for myocardial infarction and heart failure.- Role of neuropeptide Y in the regulation of kidney function.- NPY and neuron-adipocyte interactions in the regulation of metabolism.- NPY and energy homeostasis: an opportunity for novel anti-obesity therapies.- Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipidemia, insulin resistance, and obesity for life-time.- NPY and bone.- NPY in alcoholism and psychiatric disorders.- Plasticity of neuropeptide Y in the dentate gyrus after seizures, and its relevance to seizure-induced neurogenesis.- NPY and extreme stress: lessons learned from posttraumatic stress disorder.- NPY and chronic neurodegenerative disease.- Human NPY gene variants in cardiovascular and metabolic diseases.- Future directions and perspectives for therapies based on the NPY family of peptides
Series Title: EXS, 95.
Other Titles: Family of peptides in neurobiology, cardiovascular and metalobic disorders
Responsibility: Zofia Zukowska, Giora Z. Feuerstein, editors.
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