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E-mail Message: I thought you might be interested in this item at http://www.worldcat.org/oclc/241036114 Title: Nucleic acid-metal ion interactions Author: Nicholas V Hud Publisher: Cambridge, UK : RSC Publishing, ©2009. ISBN/ISSN: 9780854041954 0854041958 OCLC:241036114

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Nucleic acid-metal ion interactions

Author:	Nicholas V Hud
Publisher:	Cambridge, UK : RSC Publishing, ©2009.
Series:	RSC biomolecular sciences.
Edition/Format:	Book : EnglishView all editions and formats
Summary:	Provides a perspective on nucleic acid-metal ion interactions with an emphasis on experimental biophysical studies which will prove indispensable to biophysicists and molecular biologists.
Rating:	(not yet rated) 0 with reviews - Be the first.

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Nucleic acid metal ion interactions

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Material Type:	Internet resource
Document Type:	Book, Internet Resource
All Authors / Contributors:	Nicholas V Hud Find more information about:
ISBN:	9780854041954 0854041958
OCLC Number:	241036114
Description:	xiv, 433 p. : ill. (some col.) ; 25 cm.
Contents:	Complexes of nucleic acids with group I and II cations / Chiaolong Hsiao ... [et al.] -- Coordinative bond formation between metal ions and nucleic acid bases / Bernhard Lippert -- Sequence-specific DNA-metal ion interactions / Nicholas V. Hud and aaron E. Engelhart -- Metal ion interactions with G-quadruplex structures / Aaron E. Engelhart ... [et al.] -- Characterization of nucleic acid-metal ion binding by spectroscopic techniques / Victoria J. DeRose -- Metal ions and the thermodynamics of RNA folding / David P. Giedroc and Nicholas E. Grossoehme -- Metal ions and RNA folding kinetics / Somdeb Mitra and Michael Brenowitz -- Metal ions in RNA catalysis / John K. Frederiksen, Robert Fong and Joseph A. Piccirilli -- Polyanion models of nucleic acid-metal ion interactions / J. Michael Schurr -- Metal ion-nucleic acid interactions in disease and medicine / Ana M. Pizarro and Peter J. Sadler.
Series Title:	RSC biomolecular sciences.
Responsibility:	edited by Nicholas V. Hud.

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Nucleic reactivity

Nucleic acid-metal ion interactions
Nicholas V. Hud (Ed.)
Cambridge, UK: RSC Publishing 2009, 447pp., HB, ISBN 978-0-85404-195-4

Reviewed by Roland K.O. Sigel

Natural biochemical processes are continuously being discovered that involve RNA, ' and 'DNA has also proven in recent years to be more than a positive storehouse of information', aptly states Nicholas Hud. The book assembles in 10 chapters a large part of today's knowledge about the 'reactivity' of nucleic acids, focusing on the description of the intimate connection between metal ions and large nucleic acids.

One of the difficulties is that much of our understanding of nucleic acid-metal ion interactions rests on X-ray structure studies involving Na+, K+, Mg2+ and Ca2+. Hence, this solid state situation is strongly emphasised. Although the dynamics and kinetics of folding processes are also part of the book, it becomes clear that in the future, comprehensive solution studies of small Read more...

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