skip to content
Nucleic acids in innate immunity Preview this item
ClosePreview this item
Checking...

Nucleic acids in innate immunity

Author: Ken J Ishii; S Akira
Publisher: Boca Raton : CRC Press, ©2008.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system. Drawing  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Aufsatzsammlung
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Ken J Ishii; S Akira
ISBN: 9781420068252 1420068253
OCLC Number: 181862810
Description: xv, 286 pages : illustrations ; 25 cm
Contents: Structural analysis of toll-like receptors / by Jungwoo Choe and Ian A. Wilson --
Antiviral signaling through TLRs and RLHs / by Taro Kawai --
Recognition of virus invasion by toll-like receptors and RIG-I-like helicases / by Hiroki Kato and Osamu Takeuchi --
Characteristics of dendritic cell responses to nucleic acids / by Tsuneyasu Kaisho, Takahiro Sugiyama, and Katsuaki Hoshino --
Dendritic cells as sensors for foreign and self nucleic acids / by Anne Krug and Wolfgang Reindl --
Natural DNA recognition by toll-like receptor 9 does not reply upon CpG motifs: role of endosomal compartmentation / by Tobias Haas [and others] --
Discrimination of self and non-self DNA / by Katryn J. Stacey [and others] --
Therapeutic potential of immunosuppressive oligonucleotides expressing TTAGGG motifs / by Dennis M. Klinman [and others] --
Structure/function of IFN?-inducing CpG ODN / by Daniela Verthelyi and Montserrat Puig. Clinical development of oligodeoxynucleotide TLR9 agonists / by Julie L. Himes and Arthur M. Krieg --
Prospects for TLR9- based immunotherapy for asthma and allergy / by David Broide --
Toll-like receptors in the development of systemic autoimmune disease : in vitro artifact or in vivo paradigm? / by Ann Rothstein --
Impacts of nucleoside modification on RNA-mediated activation of toll-like receptors / by Katalin Karikó and Drew Weissman --
Activation of innate pattern recognition pathways by single-stranded ribonucleic acids / by Sandra Diebold --
RNA interference in scope of immune system / by Andrea Ablasser, Gunther Hartmann, and Veit Hornung --
Recognition of RNA and synthetic compounds by TLR7 and TLR8 / by Svetlana Hamm and Stefan Bauer --
Helicases at frontline of RNA virus recognition / by Leonid Gitlin and Marco Colonna.
Responsibility: edited by Ken J. Ishii, Shizuo Akira.
More information:

Abstract:

Explaining the roles of nucleic acids in immunity, this book describes the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/181862810> # Nucleic acids in innate immunity
    a schema:CreativeWork, schema:Book ;
    library:oclcnum "181862810" ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/766008139#Place/boca_raton> ; # Boca Raton
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/flu> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/immunreaktion> ; # Immunreaktion
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/immunity_innate_physiology> ; # Immunity, Innate--physiology
    schema:about <http://id.worldcat.org/fast/1034361> ; # Natural immunity
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/receptors_pattern_recognition_immunology> ; # Receptors, Pattern Recognition--immunology
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/rna_immunology> ; # RNA--immunology
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/autoimmunity> ; # Autoimmunity
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/self_tolerance> ; # Self Tolerance
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/dna_immunology> ; # DNA--immunology
    schema:about <http://dewey.info/class/616.079/e22/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/nucleinsauren> ; # Nucleinsäuren
    schema:about <http://id.worldcat.org/fast/1041070> ; # Nucleic acids
    schema:about <http://experiment.worldcat.org/entity/work/data/766008139#Topic/angeborene_immunitat> ; # Angeborene Immunität
    schema:bookFormat bgn:PrintBook ;
    schema:contributor <http://viaf.org/viaf/202414563> ; # S. Akira
    schema:contributor <http://viaf.org/viaf/74184789> ; # Ken J. Ishii
    schema:copyrightYear "2008" ;
    schema:datePublished "2008" ;
    schema:description "Structural analysis of toll-like receptors / by Jungwoo Choe and Ian A. Wilson -- Antiviral signaling through TLRs and RLHs / by Taro Kawai -- Recognition of virus invasion by toll-like receptors and RIG-I-like helicases / by Hiroki Kato and Osamu Takeuchi -- Characteristics of dendritic cell responses to nucleic acids / by Tsuneyasu Kaisho, Takahiro Sugiyama, and Katsuaki Hoshino -- Dendritic cells as sensors for foreign and self nucleic acids / by Anne Krug and Wolfgang Reindl -- Natural DNA recognition by toll-like receptor 9 does not reply upon CpG motifs: role of endosomal compartmentation / by Tobias Haas [and others] -- Discrimination of self and non-self DNA / by Katryn J. Stacey [and others] -- Therapeutic potential of immunosuppressive oligonucleotides expressing TTAGGG motifs / by Dennis M. Klinman [and others] -- Structure/function of IFN?-inducing CpG ODN / by Daniela Verthelyi and Montserrat Puig."@en ;
    schema:description "Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system. Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like receptors (NLR), and RIG-I-like receptors (RLR). Chapters discuss how these PRRs recognize and respond to pathogen-associated molecular patterns (PAMPs) by activating specific signaling pathways. Providing a comprehensive review of nucleic acid recognition and regulation by the innate immune system, this work reveals new directions for future research in immune modulation."@en ;
    schema:description "Clinical development of oligodeoxynucleotide TLR9 agonists / by Julie L. Himes and Arthur M. Krieg -- Prospects for TLR9- based immunotherapy for asthma and allergy / by David Broide -- Toll-like receptors in the development of systemic autoimmune disease : in vitro artifact or in vivo paradigm? / by Ann Rothstein -- Impacts of nucleoside modification on RNA-mediated activation of toll-like receptors / by Katalin Karikó and Drew Weissman -- Activation of innate pattern recognition pathways by single-stranded ribonucleic acids / by Sandra Diebold -- RNA interference in scope of immune system / by Andrea Ablasser, Gunther Hartmann, and Veit Hornung -- Recognition of RNA and synthetic compounds by TLR7 and TLR8 / by Svetlana Hamm and Stefan Bauer -- Helicases at frontline of RNA virus recognition / by Leonid Gitlin and Marco Colonna."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/766008139> ;
    schema:genre "Aufsatzsammlung"@en ;
    schema:inLanguage "en" ;
    schema:name "Nucleic acids in innate immunity"@en ;
    schema:productID "181862810" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/181862810#PublicationEvent/boca_raton_crc_press_2008> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/766008139#Agent/crc_press> ; # CRC Press
    schema:url <http://digitool.hbz-nrw.de:1801/webclient/DeliveryManager?pid=2464861&custom_att_2=simple_viewer> ;
    schema:url <http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016577299&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA> ;
    schema:url <http://catdir.loc.gov/catdir/toc/ecip085/2007047405.html> ;
    schema:workExample <http://worldcat.org/isbn/9781420068252> ;
    umbel:isLike <http://bnb.data.bl.uk/id/resource/GBA825572> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/181862810> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/766008139#Topic/angeborene_immunitat> # Angeborene Immunität
    a schema:Intangible ;
    schema:name "Angeborene Immunität"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/766008139#Topic/immunity_innate_physiology> # Immunity, Innate--physiology
    a schema:Intangible ;
    schema:name "Immunity, Innate--physiology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/766008139#Topic/receptors_pattern_recognition_immunology> # Receptors, Pattern Recognition--immunology
    a schema:Intangible ;
    schema:name "Receptors, Pattern Recognition--immunology"@en ;
    .

<http://id.worldcat.org/fast/1034361> # Natural immunity
    a schema:Intangible ;
    schema:name "Natural immunity"@en ;
    .

<http://id.worldcat.org/fast/1041070> # Nucleic acids
    a schema:Intangible ;
    schema:name "Nucleic acids"@en ;
    .

<http://viaf.org/viaf/202414563> # S. Akira
    a schema:Person ;
    schema:familyName "Akira" ;
    schema:givenName "S." ;
    schema:name "S. Akira" ;
    .

<http://viaf.org/viaf/74184789> # Ken J. Ishii
    a schema:Person ;
    schema:familyName "Ishii" ;
    schema:givenName "Ken J." ;
    schema:name "Ken J. Ishii" ;
    .

<http://worldcat.org/isbn/9781420068252>
    a schema:ProductModel ;
    schema:isbn "1420068253" ;
    schema:isbn "9781420068252" ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.