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Obesity before birth : maternal and prenatal influences on the offspring

Author: Robert H Lustig
Publisher: New York : Springer, ©2011.
Series: Endocrine updates.
Edition/Format:   Print book : EnglishView all editions and formats

Offering guidance to practitioners involved in both pre- and post-natal care, this volume explores the epidemiology and mechanisms of the relevant prenatal phenomena and investigates the role of the  Read more...


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Document Type: Book
All Authors / Contributors: Robert H Lustig
ISBN: 9781441970336 1441970339
OCLC Number: 648933267
Description: xiii, 412 pages : illustrations (some color) ; 24 cm.
Contents: Preface.- Obesity: nature or nurture?.- The contribution of heredity to clinical obesity.- Monogenetic disorders within the energy balance pathway.- Ciliary syndromes and obesity.- Genome-wide association studies and human population obesity.- Known clinical epigenetic disorders with an obesity phenotype: Prader-Willi Syndrome and the GNAS locus.- Evidence for epigenetic changes as a cause of clinical obesity.- Epigenetic changes associated with intrauterine growth retardation and adipogenesis.- Exposure to diabetes in utero, offspring growth, and risk for obesity.- Maternal weight gain during pregnancy and obesity in the offspring.- Intrauterine growth restriction, small for gestational age, and experimental obesity.- Experimental models of maternal obesity and high-fat diet during pregnancy and programmed obesity in the offspring.- High carbohydrate intake only during the suckling period results in adult-onset obesity in mother as well as offspring.- Prenatal stress, glucocorticoids, and the metabolic syndrome.- Hypothalamic maldevelopment and developmental programming.- Adipocyte development and experimental obesity.- The obesogen hypothesis of obesity: overview and human evidence.- Perinatal exposure to endocrine disrupting chemicals with estrogenic activity and the development of obesity.- The role of environmental obesogens in the obesity epidemic.
Series Title: Endocrine updates.
Responsibility: edited by Robert H. Lustig.


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From the reviews:"An interesting and timely book. ... For obstetricians, neonatologists and pediatricians in general. Recommended." (Pediatric Endocrinology Reviews (PER), Vol. 9 (2), December, 2011)

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