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One hundred years of chromosome research and what remains to be learned

Author: A Lima-de-Faria
Publisher: Dordrecht ; Boston : Kluwer Academic Publishers, 2003.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"One Hundred Years of Chromosome Research and What Remains to Be Learned offers the reader a critical analysis of the observations and experiments that shaped the last 100 years of chromosome research, as well as the ideas which prevailed during this period. Emphasis is placed on what remains to be learned, particularly in light of reality of the sequencing of DNA which leaves the previous era of chromosome research  Read more...
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Genre/Form: History
Historical Works
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: A Lima-de-Faria
ISBN: 1402014392 9781402014390
OCLC Number: 52729061
Description: vii, 219 pages : illustrations ; 31 cm
Contents: Nine Periods of Chromosome Research: 1795 to 2010 --
First Period 1795-1850 The precursors: Better microscopes allowed reaching the cell level --
Second Period 1850-1900 The pioneers: The discovery of the chromosome was a by-product of microbiology --
Third Period 1900-1930 The era of abstract genetics: Order in embryonic development led to the finding of order in inheritance --
Fourth Period 1930-1950 The impact of physics and chemistry on genetics: World War II encouraged the development of microbial genetics --
Fifth Period 1950-1970 Radioisotopes and electron microscopy became a most fruitful combination: Molecular biology received its main impulse from disciplines outside genetics --
Sixth Period 1970-1980 The mechanisms of cancer and of development were sought at the DNA level: Biotechnology emerged as a new field as genetics created its own weapons --
Seventh Period 1980-1990 Neurobiology reached the molecular level: Artificial chromosomes and gene therapy became a reality --
Eighth Period 1990-2001 The genome of humans and of other organisms was sequenced: The age of multilaboratory collaboration was established --
Ninth Period 2001-2010 The post-genome era: The task that lies ahead --
The Technology that Allowed the Study of the Chromosome: 1900 to 2001 --
From staining methods to DNA sequencing --
In Search of the Eukaryotic Chromosome --
Main stages in the discovery of the cell's structure and function --
The nucleus versus the cytoplasm. Which was most important?
Responsibility: by A. Lima-de-Faria.
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Abstract:

One Hundred Years of Chromosome Research: What Remains to be Learned, offers the reader a critical analysis of the observations and experiments that shaped the last 100 years of chromosome research,  Read more...

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"An interesting and absolutely unique work." (Bengt O. Bengtsson, Professor of Genetics, Lund University, Sweden)"I highly recommend Professor Lima-de-Faria's book because I consider it a fantastic Read more...

 
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