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Opioid peptides : medicinal chemistry

Author: Rao S Rapaka; Gene Barnett; Richard L Hawks; National Institute on Drug Abuse.
Publisher: Rockville, Md. : Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Washington, D.C. : For sale by the Superintendent of Documents, U.S. Government Publishing Office 1986.
Series: NIDA research monograph, 69.; DHHS publication, no. (ADM) 86-1454.
Edition/Format:   Print book : Conference publication : National government publication : EnglishView all editions and formats
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Genre/Form: Conference papers and proceedings
Congresses
Additional Physical Format: Online version:
Opioid peptides
(OCoLC)799703420
Material Type: Conference publication, Government publication, National government publication, Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Rao S Rapaka; Gene Barnett; Richard L Hawks; National Institute on Drug Abuse.
OCLC Number: 14266643
Notes: "Based upon papers ... from the technical review on the medicinal chemistry and molecular pharmacology of opioid peptides and the opiates which took place on September 4-6, 1984, at Bethesda, Maryland"--Page iv.
"Printed 1986"--Page 4 of cover.
Shipping list no.: 1986-751-P.
Description: viii, 376 pages : illustrations ; 23 cm.
Contents: Frontiers of research in the medicinal chemistry and molecular pharmacology of opioid peptides / Rao S. Rapaka --
Synthesis of opioid peptide analogs / John M. Stewart --
Structure-activity relationships of opioid peptides / J.S. Morley and A.S. Dutta --
Design principles : enkephalins with predictable mu/delta receptor specificity / Yasuyuki Shimohigashi --
Structure-activity relationship and pharmacology of the highly selective u-opioid agonist, morphiceptin / Kwen-Jen Chang --
Dermorphin : autonomic pharmacology and structure-activity relationships / Giora Feuerstein --
Design of conformationally constrained cyclic peptides with high delta and mu opioid receptor specificities / Victor J. Hruby --
Dehydro and cyclopropyl amino acids and peptides / Charles H. Stammer --
Affinity labels as probes for opioid receptor types and subtypes / Phillip S. Portoghese and A.E. Takemori --
Peptide conformation and biological activity : a general review with examples of approaches relevant to opioid peptide function / Dan W. Urry --
Opioid peptides : analysis of specificity and multiple binding modes through computer-aided drug design and structure-activity studies / Raoul D. Nelson [and others] --
Mechanistic structure-activity studies of peptide and nonpeptide flexible opioids : an interdisciplinary approach / Gilda H. Loew [and others] --
Conformations of opioid peptides as determined by nuclear magnetic resonance and related spectroscopies / M. Abu Khaled --
Conformational analysis of opioid peptides and the use of conformational restriction in the design of selective analogs / Peter W. Schiller --
Stereochemically constrained enkephalin analogs containing x-aminoisobutyric acid and 1-amino- cyclopentane-1-carbolylic acid / Raghuvansh Kishore and Padmanabhan Balaram --
Enkephalin conformation in solution : a perspective from vibrational spectroscopic studies / V. Renugopalakrishnan [and others] --
Conformational features of the opioid peptides in the solid state : a review of x-ray crystallographic research / Arthur Camerman and Norman Camerman --
The search for nonaddicting strong analgesics : hopes and frustrations / Sydney Archer.
Series Title: NIDA research monograph, 69.; DHHS publication, no. (ADM) 86-1454.
Responsibility: editors, Rao S. Rapaka, Gene Barnett, Richard L. Hawks.

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