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The orexin/hypocretin system : physiology and pathophysiology

Author: Seiji Nishino; Takeshi Sakurai
Publisher: Towota, N.J. : Humana Press, ©2006.
Series: Contemporary clinical neuroscience.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation. Topics
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Genre/Form: Fulltext
Internet Resources
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Seiji Nishino; Takeshi Sakurai
ISBN: 9781588294449 1588294447
OCLC Number: 62332129
Description: xii, 397 pages : illustrations ; 26 cm.
Contents: 1. History and overview of orexin/hypocretin research : from orphan GPCR to integrative physiology / Michihiro Mieda and Takeshi Sakurai --
2. Orexin and orexin receptors / Takeshi Sakurai --
3. Orexin projections and localization of orexin receptors / Jacob N. Marcus and Joel K. Elmquist --
4. Neuronal responses to hypocretin/orexin / Anthony N. van den Pol and Claudio Acuna-Goycolea --
5. Afferent system of orexin neurons / Akihiro Yamanaka --
6. Hypocretin measurements in the CSF, and blood and brain tissue : basic and clinical applications / Seiji Nishino --
7. Hypocretin receptor-activated G proteins revealed by [[superscript 35]S]GTP[gamma]S autoradiography / Rene Bernard, Ralph Lydic and Helen A. Baghdoyan.
Series Title: Contemporary clinical neuroscience.
Responsibility: edited by Seiji Nishino and Takeshi Sakurai.
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Abstract:

The Orexin/Hypocretin System provides an overview of all the recent exciting discoveries in the field as well as new findings such as ligand replacement and gene therapies in the animal models of  Read more...

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