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The organic chemistry of drug design and drug action

Author: Richard B Silverman
Publisher: San Diego : Academic Press, ©1992.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This is a new approach to the teaching of medicinal chemistry. The knowledge of the physical organic chemical basis of drug design and drug action allows the reader to extrapolate to the many related classes of drugs described in standard medicinal chemistry texts. Students gain a solid foundation to base future research endeavors upon: drugs not yet developed are thus covered! * Emphasizes the use of the principles  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Silverman, Richard B.
Organic chemistry of drug design and drug action.
San Diego : Academic Press, ©1992
(DLC) 91047041
(OCoLC)25049710
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Richard B Silverman
ISBN: 9780080571232 0080571239 1299536069 9781299536067
OCLC Number: 842936616
Reproduction Notes: Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL
Description: 1 online resource (xiv, 422 pages) : illustrations
Details: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Contents: Drug discovery, design, and development --
Receptors --
Enzymes (catalytic receptors) --
Enzyme inhibition and inactivation --
DNA and DNA -interactive agents --
Drug metabolism --
Prodrugs and drug delivery systems.
Responsibility: Richard B. Silverman.
More information:

Abstract:

This is a new approach to the teaching of medicinal chemistry. The knowledge of the physical organic chemical basis of drug design and drug action allows the reader to extrapolate to the many related classes of drugs described in standard medicinal chemistry texts. Students gain a solid foundation to base future research endeavors upon: drugs not yet developed are thus covered! * Emphasizes the use of the principles of physical organic chemistry as a basis for drug design * Discusses organic reaction mechanisms of clinically important drugs with mechanistic schemes * Uses figures and literature references extensively throughout * This text is not merely a "compilation of drugs and uses," but features selected drugs as examples of the organic chemical basis for any and all drug design applications.

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