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Ovarian cycle

Author: Gerald Litwack
Publisher: Cambridge, MA : Elsevier Ltd. : Academic Press, 2018.
Series: Vitamins and hormones, v. 107.
Edition/Format:   eBook : Document : English : First editionView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: (OCoLC)1013724845
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Gerald Litwack
ISBN: 9780128143605 0128143606
OCLC Number: 1028979398
Description: 1 online resource.
Contents: Front Cover; Ovarian Cycle; Copyright; Contents; Contributors; Preface; Chapter One: The Ovarian Cycle; 1. Introduction; 2. Ovarian Events; 2.1. Follicle Formation; 2.2. Early Stages of Follicular Growth; 2.2.1. Later Stages of Follicular Growth; 2.2.2. Ovulation; 2.2.3. Luteinization; 3. Peripheral Impact of the Ovarian Cycle; 3.1. Hypothalamus-Pituitary; 3.2. Oviduct and Uterus; 3.3. Cervical Structure and Function; 4. Breast Development; 5. Ovarian Cancer; 5.1. Epithelial Carcinomas; 5.2. Granulosa Cell Tumors; 6. Uterine, Breast, and Cervical Cancers; References Chapter Two: GnRH in the Human Female Reproductive Axis1. Introduction; 2. GnRH and GnRH Receptors; 2.1. GnRH and GnRH Isoforms; 2.2. Gonadotropin-Releasing Hormone Receptor; 3. GnRH in the Neuroendocrine Control of Female Reproductive Functions; 3.1. Control of GnRH Secretion; 3.2. GnRH in the Onset of Puberty and in the Adult Ovarian Cycle; 3.2.1. Puberty; 3.2.2. Adult Ovarian Cycle; 3.3. Dysregulation of Pulsatile GnRH Release; 3.4. Therapeutic Use of GnRH; 4. The GnRH/GnRHR System in Peripheral Female Reproductive Tissues; 4.1. Peripheral vs Central GnRHR 4.2. The GnRH/GnRHR System in the Ovary4.2.1. Follicles and Corpora Lutea; 4.2.2. Ovarian Surface Epithelium; 4.3. The GnRH/GnRHR System in the Endometrium; 5. GnRH Analogs in Reproduction; 5.1. GnRH Analogs to Stimulate the Reproductive Axis; 5.2. GnRH Analogs to Block the Reproductive Axis; 5.3. GnRH Analogs for Fertility Preservation in Female Patients Undergoing Chemotherapy; 6. Conclusions and Future Directions; Acknowledgments; References; Chapter Three: Regulation of Luteinizing Hormone Receptor mRNA Expression in the Ovary: The Role of miR-122; 1. Introduction 2. Posttranscriptional Regulation of LHR mRNA Expression2.1. LHR Expression During Ovarian Cycle Is Regulated Posttranscriptionally by an RNA-Binding Protein; 2.2. In Vitro mRNA Degradation by the LHR mRNA-Binding Protein; 2.3. Characterization of LHR mRNA-Binding Protein; 3. Role of miR-122 in LHR Expression; 3.1. LH/hCG Increases miR-122 Expression; 3.2. Inhibition of miR-122 Abrogated hCG-Induced LRBP Induction and LHR mRNA Downregulation; 3.3. miR-122 Increases LRBP Expression Through the Activation of SREBP-1a/ SREBP-2 3.4. Downregulation of miR-122 During LHR Upregulation in Response to FSH Treatment4. Conclusion and Future Directions; Acknowledgment; References; Chapter Four: The Roles of Neurokinins and Endogenous Opioid Peptides in Control of Pulsatile LH Secretion; 1. Introduction; 2. Neural Systems Critical for Episodic LH Secretion and the Negative Feedback Actions of Ovarian Steroids; 3. Kisspeptin and Episodic LH Secretion; 3.1. Role in Pulse Generation; 3.2. Role in Steroid Negative Feedback; 4. Neurokinins and Episodic LH Secretion; 4.1. Hypothalamic Anatomy of the Tachykinins
Series Title: Vitamins and hormones, v. 107.
Responsibility: series editor, Gerald Litwack.

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