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Oxidative folding of peptides and proteins
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Oxidative folding of peptides and proteins

Author: Luis Moroder; Johannes Buchner, Prof.
Publisher: Cambridge : Royal Society of Chemistry, 2009.
Series: RSC biomolecular sciences.
Edition/Format:   Book : EnglishView all editions and formats
Summary:

With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich peptides.

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Luis Moroder; Johannes Buchner, Prof.
ISBN: 9780854041480 0854041486
OCLC Number: 244653596
Notes: Includes index.
Description: xxi, 429 p. : ill. (some col.) ; 24 cm.
Contents: Thioredoxins and the regulation of redox conditions in prokaryotes / Carsten Berndt and Arne Holmgren --
Disulfide-bond formation and isomerization in prokaryotes / Goran Malojčić and Rudi Glockshuber --
The periplasm of E. coli : oxidative folding of recombinant proteins / Katharina M. Gebendorfter and Jeannette Winter --
Oxidative protein folding in mitochondria / Kail Hell and Walter Neupert --
Oxidative folding in the endoplasmic reticulum / Seema Chakravarthi, Catherine E. Jessop and Neil J. Bulleid --
The Ero1 sulfhydryl oxidase and the oxidizing potential of the endoplasmic reticulum / Deborah Fass and Carolyn S. Sevier --
Eukaryotic protein disulfide-isomerases and their potential in the production of disulfide-bonded protein products : what we need to know but do not! / Robert B. Freedman --
Cellular responses to oxidative stress / Marianne Ilbert, Caroline Kumsta and Ursula Jakob --
The role of disulfide bonds in protein folding and stability / Matthias Johannes Feige and Johannes Buchner --
Strategies for the oxidative in vitro refolding of disulfide-bridge-containing proteins / Rainer Rudolph and Christian Lange --
Redox potentials of cysteine residues in peptides and proteins : methods for their determination / Dallas L. Rabenstein --
Engineered disulfide bonds for protein design / Luis Moroder, Hans-Jürgen Musiol and Christian Renner --
Selenocysteine as a probe of oxidative protein folding / Joris Beld, Kenneth J. Woycechowsky and Donald Hilvert --
Oxidative folding of single-stranded disulfide-rich peptides / Grzegorz Bulaj and Aleksandra Walewska --
Regioselective disulfide formation / Knut Adermann and Kleomenis Barlos --
Folding motifs of cystine-rich peptides / Norelle L. Daly and David J. Craik --
Double-stranded cystine peptides / John D. Wade --
Multiple-strand cystine peptides / Marion G. Götz, Hans-Jürgen Musiol and Luis Moroder --
Cystine-based scaffolds for functional miniature proteins / Rudolf K. Allemann --
Selenocystine peptides : synthesis, folding and applications / Markus Muttenthaler and Paul F. Alewood.
Series Title: RSC biomolecular sciences.
Responsibility: editors, Luis Moroder and Johannes Buchner.

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Oxidative folding of peptides and proteins

Luis Moroder and Johannes Buchner (Eds.)
RSC Publishing, Cambridge, UK, 2009, 430pp, (HB) ISBN 9780854041480

This book describes the enzymes involved in the correct oxidative folding of cysteine-containing proteins in prokaryotes and eukaryotes. The copying of these enzymes for successful in vivo folding of proteins (including in vitro folding of synthetic replicates) and the role disulfide bridges play in the folding and stability of proteins and peptides are also discussed.

Chemistry World, 2009, 6(7), p. 62 Read more...

 
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