The magical practices and potions of the Land of Oz is the thread running through The Patchwork Girl. The story begins with a visit by a young Munchkin lad, Ojo the Unlucky, who with his Unc Nunkie visit a reclusive magician, Dr. Pipt. The old sorcerer has just completed the six year task of brewing a spoonful of the Powder of Life, and is preparing to administer it to a life-sized rag doll made by his wife Margolotte. The intent is to create a servant to help his wife in her chores, but unbeknownst to the magician, Ojo doctors the doll's brains. In the confusion that erupts as the Powder of Life performs its miracle, Margolotte and Unc Nunkie are turned into marble statues and the Patchwork Girl is brought to life quite unfit to ever be a servant. To restore life to the two hapless victims, Ojo undertakes a quest to find the ingredients for an antidote to the enchantment, accompanied by the Patchwork Girl and the Glass Cat, another creation of Dr. Pipt. A series of adventures ensue, as they brave new challenges and meet new and amazing peoples and lands in their hunt for the magical ingredients. Through the trials of this grand quest Ojo learns that he is no longer presumed to be ill-fated by circumstance of birth, and is known henceforth as Ojo the Lucky.