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The pathogenic spirochetes : strategies for evasion of host immunity and persistence

Author: Monica E Embers
Publisher: New York : Springer, ©2012.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Embers, Monica E.
The Pathogenic Spirochetes
Dordrecht : Springer,c2012
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Monica E Embers
ISBN: 9781461454045 1461454042
OCLC Number: 828303026
Description: 1 online resource (272 p.) : ill. (some col.)
Contents: Invasion and Dissemination --
Treponema pallidum Dissemination; Facilitating Immune Evasion and Bacterial Persistence / Simon Houston, Caroline E. Cameron --
Immunoseclusion and Chronic Infection by Borrelia burgdorferi / Robert D. Gilmore Jr. --
Immune Evasion --
Treponema denticola: FhbB, Dentilisin, Complement Evasion and the Paradox of Factor H Cleavage / John V. McDowell, Daniel P. Miller, Katherine L. Mallory --
Borrelial Complement-Binding Proteins / Peter Kraiczy, Reinhard Wallich --
Treponema pallidum Repeat (tpr) Genes and Antigenic Variation / Lorenzo Giacani, Arturo Centurion-Lara --
Antigenic Variation of VlsE in Borrelia burgdorferi / Troy Bankhead --
Modulation of Cytokine Signaling by B. burgdorferi / Vida A. Dennis, Aarti Gautam, Saurabh Dixit --
Leptospira: Invasion, Pathogenesis and Persistence / Syed M. Faisal, Sean P. McDonough, Yung-Fu Chang --
Immune Resistance by Relapsing Fever Spirochetes / Monica E. Embers, Job E. Lopez --
Persistence --
Neuroborreliosis Caused by Borrelia burgdorferi: Possible Role of Glial Cells / Mario T. Philipp, Geeta Ramesh, Geetha Parthasarathy --
Antibiotic Resistance in Treponema pallidum subsp. pallidum, the Syphilis Agent / Lola V. Stamm --
Borrelia burgdorferi Persistence Post-antibiotic Treatment / Monica E. Embers, Stephen W. Barthold. Part I. Invasion and dissemination --
Part II. Immune evasion --
Part III. Persistence.
Responsibility: Monica E. Embers, editor.
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Abstract:

This book explores the mechanisms by which Spirochetal pathogens persist in a healthy immune-competent host, including the direct and indirect suppression of host immune signals, phase and antigenic  Read more...

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