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Pharmaceutical enzymes

Author: Albert Lauwers; Simon Scharpé
Publisher: New York : Marcel Dekker, ©1997.
Series: Drugs and the pharmaceutical sciences, v. 84.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Offers comprehensive, interdisciplinary analyses of the pharmaceutical enzyme field from molecular biology to clinical pharmacology. Emphasizing pharmacology and clinical impact, this book discusses  Read more...

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Document Type: Book
All Authors / Contributors: Albert Lauwers; Simon Scharpé
ISBN: 0824793757 9780824793753
OCLC Number: 36917079
Description: viii, 401 pages : illustrations ; 24 cm.
Contents: pt. 1. Bioavailability of pharmaceutical enzymes --
Biopharmaceuticl aspects of enzyme absorption --
The endothelium monolayer: barrier to enzyme and drug delivery --
pt. 2. Tailoring of pharmaceutical enzymes --
Enzyme-albumin conjugates: advantages and problems with targeting --
Acyl enzymes as prodrugs --
Molecular modeling of pharmaceutically important targets --
pt. 3. Biochemical and pharmacological properties --
The cysteine proteinases from the latex of Carica papaya L --
Bromelain --
Hyaluronidase --
Pancreatic enzyme replacement --
I-asparaginase: an essential antineoplastic drug --
Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease --
Deoxyribonuclease I --
Therapeutic protein inhibitors of elastase --
pt. 4. Standardization and methodology --
Good standardization practices --
Assays.
Series Title: Drugs and the pharmaceutical sciences, v. 84.
Responsibility: edited by Albert Lauwers, Simon Scharpé.
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"a timely resource on the latest developments in the biotechnology development of pharmaceutical enzymes as therapeutic agents. "-Doody's Health Sciences Book Review Journal

 
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