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Pharmacogenomics and personalized medicine

Author: Nadine Cohen
Publisher: Totowa, NJ : Humana Press, ©2008.
Series: Methods in pharmacology and toxicology.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
With the multitude of challenges facing the pharmaceutical research and development process, the industry is exploring the relationships between human genetics and drug responsiveness, susceptibility to disease and disease severity. This text provides guidance for conducting pharmacogenomic research from discovery to the market.
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Nadine Cohen
ISBN: 9781934115046 1934115045 9781597454391 1597454397 1617379212 9781617379215
OCLC Number: 213114046
Description: xv, 509 pages : illustrations ; 25 cm.
Contents: Challenges, opportunities, and evolving landscapes in pharmacogenomics and personalized medicine : an industry perspective / Nadine Cohen and Theresa Frangiosa --
Implementation of pharmacogenomic sample collection in clinical trials / Deborah Sokol Ricci and Monique Franc --
Pharmacogenomics : the regulatory environment and labeling implications / Myong-Jin Kim [and others] --
Applications of pharmacogenomics in drug discovery / Duncan McHale --
Applications of pharmacogenomics in clinical trials / Monique Franc --
Pharmacogenomics applications in drug metabolism : from genotyping to drug label-challenges? / Ann K. Daly --
The genetics of adverse drug reactions : promises and problems / Martin Armstrong --
Strategies and resources for marker selection and genotyping in genetic association studies / Nicole Soranzo, Dong-Jing Fu, and Qingqin S. Li --
Study design and statistical issues in pharmacogenetics research : from candidate genes to genome-wide screens / Nicholas J. Schork, Nathalie Malo, and Eric J. Topol --
Holy SNP, Batman! / Reyna Favis --
Predictive biomarker classifiers in the design of pivotal clinical trials / Richard Simon --
Translation of biomarkers into clinical utility / William L. Trepicchio and George Mulligan --
Pharmacogenomic study feasibility assessment and pharmaceutical business decision-making / Monique Franc and Theresa Frangiosa --
Co-development of drugs and pharmacogenomics-based diagnostics in oncology / Jeffrey S. Ross --
Pharmacogenomics applications in epilepsy / Chantal Depondt --
Pharmacogenomics in Alzheimer's disease / Ramón Cacabelos --
Pharmacogenomics applications in psychiatric disorders / Todd Lencz and Anil K. Malhotra --
Pharmacogenomics in HIV disease / Amalio Telenti --
Pharmacogenomics and cardiovascular drugs / Gérard Siest [and others] --
Pharmacogenomic applications in children / Susan F.A. Grant and Hakon Hakonarson --
Pharmacogenomics of rare and monogenic disorders / Paul D. Maher.
Series Title: Methods in pharmacology and toxicology.
Responsibility: Nadine Cohen, editor.
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Abstract:

Leading experts from the pharmaceutical industry, the scientific community and the government provide guidance for conducting pharmacogenomic research from discovery to the market, while presenting a  Read more...

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From the reviews:"The purpose is to provide a practical and integrative view of the application of pharmacogenomics to personalized medicine. ... the information is valuable for scientists in Read more...

 
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