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Pharmacogenomics : methods and protocols

Author: Federico Innocenti
Publisher: Totowa, N.J. : Humana Press, ©2005.
Series: Methods in molecular biology (Clifton, N.J.), v. 311.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Pharmacogenomics holds the promise of drugs tailor-made to an individual's genetic makeup for greater efficacy and safety. In Pharmacogenomics: Methods and Protocols, expert researchers and physician/clinicians describe in detail the newest and most common technologies now used in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Pharmacogenomics.
Totowa, N.J. : Humana Press, ©2005
(DLC) 2005010328
(OCoLC)59098714
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Federico Innocenti
ISBN: 9781592599578 1592599575
OCLC Number: 209852871
Description: 1 online resource (x, 214 pages) : illustrations.
Contents: Pharmacogenomics : historical perspective and current status / Werner Kalow --
Transfection assays with allele-specific constructs : functional analysis of UDP-glucuronosyltransferase variants / Hideto Jinno [and others] --
Snapshot of the allele-specific variation in human gene expression / Hai Yan --
Genome-wide analysis of allele-specific gene expression using oligo microarrays / Maxwell P. Lee --
HaploChIP : an in vivo assay / Julian Charles Knight --
Aspects influencing genotyping method selection / Peter Imle --
Denaturing high-performance liquid chromatography for mutation detection and genotyping / Donna Lee Fackenthal, Pei Xian Chen, and Soma Das. Pyrosequencing of clinically relevant polymorphisms / Sharon Marsh [and others] --
Kinetic fluorescence-quenching detection assay for allele frequency estimation / Ming Xiao and Pui-Yan Kwok --
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry / Matthias Wjst and Dirk van den Boom --
Fluorescence-based fragment size analysis / Peter Imle --
Single-nucleotide polymorphism genotyping in deoxyribonucleic acid pools / Ian Craig [and others] --
TaqMan genotyping of insertion/deletion polymorphisms / Renato Robledo, William R. Beggs, and Patrick K. Bender --
PharmGKB : the pharmacogenetics and pharmacogenomics knowledge base / Caroline F. Thorn, Teri E. Klein, and Russ B. Altman --
Systems for the management of pharmacogenomic information / Alexander Sturn [and others].
Series Title: Methods in molecular biology (Clifton, N.J.), v. 311.
Responsibility: edited by Federico Innocenti.
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Abstract:

Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo  Read more...

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