skip to content
Pharmacoresistance in Epilepsy : From Genes and Molecules to Promising Therapies Preview this item
ClosePreview this item

Pharmacoresistance in Epilepsy : From Genes and Molecules to Promising Therapies

Author: Luisa Rocha; Esper A Cavalheiro
Publisher: New York, NY : Springer New York : Imprint: Springer, 2013.
Edition/Format:   Print book : Document   Computer File : EnglishView all editions and formats

This book examines all issues related to pharmacoresistance in epilepsy and describes recent developments in the pathogenesis and treatment of this disorder. It also details novel therapeutic  Read more...


(not yet rated) 0 with reviews - Be the first.

More like this


Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...


Additional Physical Format: Printed edition:
Pharmacoresistance in Epilepsy
Material Type: Document
Document Type: Book, Computer File
All Authors / Contributors: Luisa Rocha; Esper A Cavalheiro
ISBN: 9781461464648 1461464641
OCLC Number: 940530091
Description: 1 online resource (XII, 329 p. 40 illus., 26 illus. in color.)
Contents: Pharmacoresistance and Epilepsy.- Genes involved in pharmacoresistant epilepsy.- Pathological oscillations in the pharmacoresistant epileptic brain.- Molecular mechanisms of pharmacoresistant epilepsy.- Modifications in the seizures susceptibility by excitotoxic neuronal damage and its possible relationship with the pharmacoresistance.- Intracellular pathways associated with neuronal survival and death in epilepsy.- The role of JNK pathway in the process of excitotoxicity induced by epilepsy and neurodegeneration.- Proteomics-based strategy to identify biomarkers and pharmacological targets in temporal lobe epilepsy.- Abnormalities of GABA system and human pharmacoresistant epilepsy.- Pharmacoresistant epilepsy and immune system.- Contribution of the antiepileptic drug administration regime in the development and/or establishment of pharmacoresistant epilepsy.- Experimental models to study pharmacoresistance in epilepsy.- Resistance to epileptogenesis in the Neotropical rodent Proechimys.- On the development of new antiepileptic drugs for the treatment of pharmacoresistant epilepsy - Different approaches to different hypothesis.- Modulating P-glycoprotein regulation as a therapeutic strategy for pharmacoresistant epilepsy.- Vagus Nerve Stimulation for Intractable Seizures.- The role of neuromodulation in the treatment of refractory epilepsy.- Transcranial magnetic stimulation and refractory partial epilepsy.- Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.- Physical exercise as a strategy to reduce seizure susceptibility.
Responsibility: edited by Luisa Rocha, Esper A. Cavalheiro.
More information:


User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...


Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data

Primary Entity

<> # Pharmacoresistance in Epilepsy From Genes and Molecules to Promising Therapies
    a schema:Book, schema:CreativeWork, schema:MediaObject ;
   library:oclcnum "940530091" ;
   library:placeOfPublication <> ; # New York, NY
   library:placeOfPublication <> ;
   schema:about <> ; # Neurosciences
   schema:about <> ; # Medicine
   schema:about <> ;
   schema:about <> ; # Pharmacology/Toxicology
   schema:about <> ; # Biomedicine
   schema:about <> ; # Toxicology
   schema:about <> ; # Neurology
   schema:bookFormat bgn:PrintBook ;
   schema:contributor <> ; # Esper A. Cavalheiro
   schema:creator <> ; # Luisa Rocha
   schema:datePublished "2013" ;
   schema:exampleOfWork <> ;
   schema:inLanguage "en" ;
   schema:isSimilarTo <> ;
   schema:name "Pharmacoresistance in Epilepsy From Genes and Molecules to Promising Therapies" ;
   schema:numberOfPages "329" ;
   schema:productID "940530091" ;
   schema:publication <> ;
   schema:publisher <> ; # Imprint: Springer
   schema:publisher <> ; # Springer New York
   schema:workExample <> ;
   schema:workExample <> ;
   wdrs:describedby <> ;

Related Entities

<> # Imprint: Springer
    a bgn:Agent ;
   schema:name "Imprint: Springer" ;

<> # Springer New York
    a bgn:Agent ;
   schema:name "Springer New York" ;

<> # Esper A. Cavalheiro
    a schema:Person ;
   schema:familyName "Cavalheiro" ;
   schema:givenName "Esper A." ;
   schema:name "Esper A. Cavalheiro" ;

<> # Luisa Rocha
    a schema:Person ;
   schema:familyName "Rocha" ;
   schema:givenName "Luisa" ;
   schema:name "Luisa Rocha" ;

<> # Pharmacology/Toxicology
    a schema:Intangible ;
   schema:name "Pharmacology/Toxicology" ;

    a schema:CreativeWork ;
   rdfs:label "Pharmacoresistance in Epilepsy" ;
   schema:description "Printed edition:" ;
   schema:isSimilarTo <> ; # Pharmacoresistance in Epilepsy From Genes and Molecules to Promising Therapies

    a schema:ProductModel ;
   schema:isbn "1461464641" ;
   schema:isbn "9781461464648" ;

Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.