passa ai contenuti
Phosphoinositides and disease Anteprima di questo documento
ChiudiAnteprima di questo documento
Stiamo controllando…

Phosphoinositides and disease

Autore: Marco Falasca
Editore: Dordrecht ; New York : Springer, ©2012.
Serie: Current topics in microbiology and immunology, v. 362.
Edizione/Formato:   eBook : Document : EnglishVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
Phosphoinositides (PIs) are minor components of cellular membranes that play critical regulatory roles in several intracellular functions. This book describes the main enzymes regulating the turnover of each of the seven PIs in mammalian cells, some of their intracellular functions and some evidence of their involvement in human diseases. Due to the complex inter-relation between the distinct PIs and the plethora of  Per saperne di più…
Voto:

(non ancora votato) 0 con commenti - Diventa il primo.

Soggetti
Altri come questo

 

Trova una copia online

Collegamenti a questo documento

Trova una copia in biblioteca

&AllPage.SpinnerRetrieving; Stiamo ricercando le biblioteche che possiedono questo documento…

Dettagli

Genere/forma: Electronic books
Informazioni aggiuntive sul formato: Print version:
Phosphoinositides and disease.
(DLC) 2012950382
(OCoLC)819537111
Tipo materiale: Document, Risorsa internet
Tipo documento: Internet Resource, Computer File
Tutti gli autori / Collaboratori: Marco Falasca
ISBN: 9789400750258 9400750250
Numero OCLC: 817799592
Descrizione: 1 online resource (vi, 318 pages) : illustrations.
Contenuti: Table of contents.- An introduction to Phosphoinositides, Tania Maffucci.- Phosphoinositides and Cardiovascular Diseases, Emilio Hirsch.- Phosphoinositides in Insulin Action and Diabetes, Alan Saltiel.- Phosphoinositides in neuroexocytosis and neuronal diseases, Frederic Meunier.- Effects of Phosphoinositides and their derivatives on Membrane Morphology and function, Banafshe Larijani.- Molecular analysis of protein-phosphoinositide interactions, Tatiana Kutateladze.- PIKfyve and its lipid products in health and in sickness, Assia Shisheva.- Class I phosphoinositide 3-kinases in normal and pathologic haematopoietic cells, Bernard Payrastre.- The diverse functions of Phosphatidylinositol Transfer proteins, Shamshad Cockcroft.- Myotubularin phosphoinositide phosphatases in human diseases, Jocelyn Laporte.- Nuclear PI-PLC beta1 and Myelodysplastic Syndromes: from bench to clinics, Lucio Cocco.- Inositol polyphosphate phosphatases in human disease, Christina Mitchell.- Index.
Titolo della serie: Current topics in microbiology and immunology, v. 362.
Responsabilità: Marco Falasca, editor.
Maggiori informazioni:

Abstract:

Phosphoinositides (PIs) are minor components of cellular membranes that play critical regulatory roles in several intracellular functions. This book describes the main enzymes regulating the turnover of each of the seven PIs in mammalian cells, some of their intracellular functions and some evidence of their involvement in human diseases. Due to the complex inter-relation between the distinct PIs and the plethora of functions that they can regulate inside a cell, this book is not meant to be a comprehensive coverage of all aspects of PIs signalling but rather an overview on the current state of the field and where it could go from here. Phosphoinositide and inositol phosphates interact with and modulate the recruitment and activation of key regulatory proteins and in doing so control diverse functions including cell growth and proliferation, apoptosis, cytoskeletal dynamics, insulin action, vesicle trafficking and nuclear function. Initially, inositide signaling was limited to the PLC pathway; however, it is now clear that all the seven phosphoinositides and more than 30 different inositol phosphates likely have specific signaling functions. Moreover there is a growing list of proteins that are regulated by inositol signaling. This has raised the question as to how inositol signaling can control diverse processes and yet maintain signaling specificity. Controlling the levels of inositol signaling molecules and their subcellular compartmentalisation is likely to be critical. This meeting will bring together scientists from different backgrounds to discuss how understanding inositol signaling may be used to target complex human diseases that manifest themselves when inositol signaling is deregulated.

Commenti

Commenti degli utenti
Recuperando commenti GoodReads…
Stiamo recuperando commenti DOGObooks

Etichette

Diventa il primo.
Conferma questa richiesta

Potresti aver già richiesto questo documento. Seleziona OK se si vuole procedere comunque con questa richiesta.

Dati collegati


<http://www.worldcat.org/oclc/817799592>
library:oclcnum"817799592"
library:placeOfPublication
library:placeOfPublication
library:placeOfPublication
owl:sameAs<info:oclcnum/817799592>
rdf:typeschema:Book
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
<http://id.loc.gov/authorities/subjects/sh85101107>
rdf:typeschema:Intangible
schema:name"Phosphoinositides--Pathophysiology."@en
schema:name"Phosphoinositides."@en
schema:about
schema:bookFormatschema:EBook
schema:contributor
schema:copyrightYear"2012"
schema:datePublished"2012"
schema:description"Phosphoinositides (PIs) are minor components of cellular membranes that play critical regulatory roles in several intracellular functions. This book describes the main enzymes regulating the turnover of each of the seven PIs in mammalian cells, some of their intracellular functions and some evidence of their involvement in human diseases. Due to the complex inter-relation between the distinct PIs and the plethora of functions that they can regulate inside a cell, this book is not meant to be a comprehensive coverage of all aspects of PIs signalling but rather an overview on the current state of the field and where it could go from here. Phosphoinositide and inositol phosphates interact with and modulate the recruitment and activation of key regulatory proteins and in doing so control diverse functions including cell growth and proliferation, apoptosis, cytoskeletal dynamics, insulin action, vesicle trafficking and nuclear function. Initially, inositide signaling was limited to the PLC pathway; however, it is now clear that all the seven phosphoinositides and more than 30 different inositol phosphates likely have specific signaling functions. Moreover there is a growing list of proteins that are regulated by inositol signaling. This has raised the question as to how inositol signaling can control diverse processes and yet maintain signaling specificity. Controlling the levels of inositol signaling molecules and their subcellular compartmentalisation is likely to be critical. This meeting will bring together scientists from different backgrounds to discuss how understanding inositol signaling may be used to target complex human diseases that manifest themselves when inositol signaling is deregulated."@en
schema:exampleOfWork<http://worldcat.org/entity/work/id/1184406615>
schema:genre"Electronic books."@en
schema:inLanguage"en"
schema:name"Phosphoinositides and disease"@en
schema:publisher
schema:url
schema:url<http://site.ebrary.com/id/10617886>
schema:url<http://dx.doi.org/10.1007/978-94-007-5025-8>
schema:url<http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=511420>
schema:workExample

Content-negotiable representations

Chiudi finestra

Per favore entra in WorldCat 

Non hai un account? Puoi facilmente crearne uno gratuito.