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Platelet proteomics : principles, analysis, and applications

Author: Ángel García; Yotis A Senis; Wiley InterScience (Online service)
Publisher: Hoboken, N.J. : John Wiley & Sons, ©2011.
Series: Wiley-Interscience series on mass spectrometry.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs)  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Platelet proteomics.
Hoboken, N.J. : John Wiley & Sons, ©2011
(OCoLC)730519654
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Ángel García; Yotis A Senis; Wiley InterScience (Online service)
ISBN: 9780470940297 0470940298 9780470940280 047094028X
OCLC Number: 746326260
Description: 1 online resource (xx, 403 pages) : illustrations.
Contents: Platelets and their role in thrombotic and cardiovascular disease : the impact of proteomic analysis / by Ronald Stanley & Jon Gibbins --
Mass spectrometry-based proteomics : general overview, and PTMS analysis in the context of platelet research / by Julia Burkhart & Albert Sickmann --
Sample preparation variables in platelet proteomics for biomarker research / by Maria Zellner and Rudolf Oehler --
Two-dimensional gel electrophoresis : basic principles and application to platelet signaling studies / by Ángel García --
The platelet membrane proteome / by Yotis A. Senis --
Organellar proteomics and the analysis of the platelet releasate / by James McRedmond --
The platelet microparticle proteome / by David Smalley --
N-terminal cofradic analysis of the human platelet proteome / by Kris Gevaert et al. --
Sage to study the platelet and megakaryocyte transcriptome / by Mike Tomlinson --
The application of microarray analysis and its integration with proteomics to study platelet-associated disorders / by Wadie Bahou and Dimitri Gnatenko --
Platelet functional genomics / by Isabelle I. Salles et al. --
The systems biology to study platelet-related bleeding disorders / by Jan Willem Akkerman and Bernard de Bono --
Platelet proteomics in transfusion medicine / by Andreas Greinacher & Thomas Thiele --
Cardiovascular proteomics / by Fernando Vivanco et al.
Series Title: Wiley-Interscience series on mass spectrometry.
Responsibility: edited by Ángel García, Yotis A. Senis.

Abstract:

The purpose of the book is to introduce platelets, and theirfunctional role in thrombotic and cardiovascular disease,justifying the relevance of platelet proteomics research. Focusthen shifts to the  Read more...

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