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Polymer drugs in the clinical stage : advantages and prospects

Author: H Maeda; Alexander V Kabanov; K Kataoka
Publisher: New York ; London : Kluwer Academic/Plenum, ©2003.
Series: Advances in experimental medicine and biology, v. 519.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

Cancer targeted drug delivery is another focused area of this volume because of the important nature of EPR-effect of polymer drugs in tumor. The concept of "Polymer drugs" here is limited to  Read more...

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Genre/Form: Electronic books
Conference papers and proceedings
Congresses
Additional Physical Format: Print version:
Polymer drugs in the clinical stage.
New York ; London : Kluwer Academic/Plenum, ©2003
(DLC) 2003266837
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: H Maeda; Alexander V Kabanov; K Kataoka
ISBN: 9780306474712 0306474719
OCLC Number: 646723397
Description: 1 online resource (viii, 224 pages) : illustrations.
Contents: Challenges in Polymer Therapeutics: State of the Art and Prospects of Polymer Drugs; A. Kabanov, T. Okano. Factors and Mechanism of 'EPR' Effect and the Enhanced Antitumor Effects of Macromolecular Drugs Including SMANCS; Jun Fang, T.Sawa, H. Maeda. PEG-Adenosine Deaminase and PEG-Asparaginase; F. Davis. Peginterferon alfa-2a (40KD): A Potent Long-Acting Form of Interferon alfa-2a for the Treatment of Hepatitis C; M. Modi, M. Lamb, M. Shiomi. PEG-Methioninase; R.Hoffman. Poly-(L)-Glutamic Acid-Paclitaxel (CT-2103)[XYOTAX (R)], a Biodegradable Polymeric Drug Conjugate: Characterization, Preclinical Pharmacology, and Preliminary Clinical Data; J. Singer, B. Baker, P. De Vries, A. Kumar, S. Shaffer, E. Vawter, M. Bolton, P. Garzone. HPMA Copolymer Delivery of Chemotherapy and Photodynamic Therapy in Ovarian Cancer; C.M. Peterson, Jane-Guo Shiah, Yongen Sun, P. Kopeckova, T. Minko, R. Straight, J. Kopecek. Drug-HPMA-HuIg Conjugates Effective Against Human Solid Cancer; B. Rihova, J. Strohalm, K. Kubackova, M. Jelinkova, L. Rozprimova, M. Sirova, D. Plocova, T. Mrkvan, M. Kovar, J. Pokorna, T. Etrych, K. Ulbrich#. CM-Dextran-Polyalcohol-Camptothecin Conjugate: DE310 with a Novel Carrier System and its Preclinical Data; K. Inoue, E. Kumazawa, H. Kuga, H. Susaki, N. Masubuchi, T. Kajimura. Polymeric Micelle Drug Carrier Systems: PEG-PAsp(Dox) and Second Generation of Micellar Drugs; N. Nishiyama, K. Kataoka. An Interim Analysis of Phase I Clinical Trial of MCC-465, a Doxorubicin (DXR) Encapsulated in PEG-immunoliposome, in Patients with Metastatic Stomach Cancer; Y. Matsumura. Polymer Conjugates for Imaging; A. Perkins. S-Nitrosylated Polyethylene Glycol-conjugated Hemoglobin Derivative as a Candidate Material for Oxygen Therapeutics; K.Nakai, I. Sakuma, H. Togashi, M.Yoshioka, T. Sugawara, H. Satoh, A. Kitabatake. Index.
Series Title: Advances in experimental medicine and biology, v. 519.
Responsibility: edited by Hiroshi Maeda, Alexander Kabanov, Kazurori [i.e. Kazunori] Kataoka.

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