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Polymers As Aids In Organic Chemistry.

Author: N K Mather
Publisher: Oxford : Elsevier Science, 1980.
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Polymers As Aids In Organic Chemistry.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Mather, N.K.
Polymers As Aids In Organic Chemistry.
Oxford : Elsevier Science, ©1980
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: N K Mather
ISBN: 9780323141192 0323141196
OCLC Number: 836402238
Notes: XIII. Synthesis of Oligoribonucleotides on Polymer Supports.
Description: 1 online resource (271 pages)
Contents: Front Cover; Polymers as Aids in Organic Chemistry; Copyright Page; Table of Contents; Synthesis; Preface; Chapter 1. Introduction; I. History; II. Development of Polymer Science and Technology; III. Definition and Classification of Polymers; IV. Preparation of Synthetic Polymers; V. Properties of Polymers; VI. Synthesis of Functionalized Polymers; VII. Types of Functionalized Polymers; VIII. General Chemical Reactions of Polymers; IX. Polymers as Aids in Organic Synthesis; X. Kinetics of Polymer-Analogous Reactions; XI. Literature on Solid-Phase Synthesis; References. Chapter 2. Polymeric Support MaterialsI. Introduction; II. Styrene-Based Polymers; III. Functionalization of Styrene-Based Polymers via Chloromethylation and Other Methods; IV. Miscellaneous Polymer Supports; References; Chapter 3. Determination of Functionalization in Polymer Supports; I. Introduction; II. Chemical Methods for Functional Group Analysis of Polymers; III. Physical and Physicochemical Methods of Determining Functional Groups in Polymers; IV. Physical and Chemical Nature of Immobilization of Reactive Sites on Polymers. V. Use of Radiolabeled Reagents to Follow the Changes in Resin FunctionalitiesVI. Reporting of Results; References; Chapter 4. Polypeptide Synthesis on Polymer Supports; I. Introduction and History; II. Basic Principles of Merrifield, s Solid-Phase Peptide Synthesis; III. Supports for Solid-Phase Peptide Synthesis; IV. Linkage of the First Amino Acid to the Polymer; V. Protecting Groups Used in Solid-Phase Peptide Synthesis; VI. Coupling of Successive Amino Acids to Resin-Bound Amino Acids; VII. Cleavage of the Resin-Peptide Bond; VIII. Monitoring of Solid-Phase Peptide Synthesis. IX. Automation in Solid-Phase Peptide SynthesisX. Racemization Problems in Solid-Phase Peptide Products; XI. Purification of Solid-Phase Peptide Products; XII. Problems in Solid-Phase Synthesis; XIII. Solid-Phase Coupling of N-Carboxylanhydrides (NCA); XIV. Solid-Phase Synthesis Using Side-Chain Functionalities for Attachment to Polymers and Bidirectional Extension of Peptide Chains; XV. Fragment Condensation Strategy in Solid-Phase Peptide Synthesis; References; Chapter 5. Oligonucleotide Synthesis on Polymer Supports; I. Introduction. II. General Principles of Solid-Phase Oligonucleotide SynthesisIII. Polymer Supports; IV. Functionalization of Polymer Supports; V. Strategies Used for Oligonucleotide Synthesis on Polymer Supports; VI. Protection of Reactive Groups; VII. Cleavage of the Protecting Groups; VIII. Attachment of the Polymeric Carrier to the Nucleotide or Nucleoside; IX. Elongation of the Nucleotide Chain on the Polymer Support; X. Cleavage of the Polymer-Nucleoside/Nucleotide Bond; XI. Monitoring in Polymer-Supported Oligonucleotide Synthesis; XII. Purification of Synthetic Oligonucleotides.

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Polymers As Aids In Organic Chemistry.

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