skip to content
Preclinical development handbook. / ADME and biopharmaceutical properties Preview this item
ClosePreview this item
Checking...

Preclinical development handbook. / ADME and biopharmaceutical properties

Author: Shayne C Gad; Wiley InterScience (Online service)
Publisher: Hoboken, N.J. : Wiley-Interscience, ©2008.
Series: Pharmaceutical Development Series.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book gives the professional pharmaceutical scientist a basic and comprehensive tool to facilitate the preclinical development process by bringing together an overview of the preclinical process and a compendium of methods and techniques that need to.
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

 

Find a copy online

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Handbooks and manuals
Handbooks, manuals, etc
Additional Physical Format: Print version:
Preclinical development handbook. ADME and biopharmaceutical properties.
Hoboken, N.J. : Wiley-Interscience, ©2008
(DLC) 2008003750
(OCoLC)176895587
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Shayne C Gad; Wiley InterScience (Online service)
ISBN: 9780470249055 0470249056 9780470249024 0470249021 1281237418 9781281237415
OCLC Number: 214281935
Description: 1 online resource (xv, 1329 pages) : illustrations
Contents: Preface. 1 Modeling and Informatics in Drug Design ( Prasad V. Bharatam, Smriti Khanna, and Sandrea M. Francis ). 2 Computer Techniques: Identifying Similarities Between Small Molecules ( Peter Meek, Guillermo Moyna, and Randy Zauhar ). 3 Protein-Protein Interactions ( Kamaljit Kaur, Dipankar Das, and Mavanur R. Suresh ). 4 Method Development for Preclinical Bioanalytical Support ( Masood Khan and Naidong Weng ). 5 Analytical Chemistry Methods: Developments and Validation ( Izet M. Kapetanovic and Alexander V. Lyubimov ). 6 Chemical and Physical Characterizations of Potential New Chemical Entity ( Adegoke Adeniji and Adeboye Adejare ). 7 Permeability Assessment ( Srinivas Ganta, Puneet Sharma, and Sanjay Garg ). 8 How and Where Are Drugs Absorbed? ( Marival Bermejo and Isabel Gonzalez-Alvarez ). 9 Absorption of Drugs after Oral Administration ( Luis Granero and Ana Polache ). 10 Distribution: Movement of Drugs through the Body ( Jayanth Panyam and Yogesh Patil ). 11 The Blood-Brain Barrier and Its Effect on Absorption and Distribution ( A. G. de Boer and P. J. Gaillard ). 12 Transporter Interactions in the ADME Pathway of Drugs ( Yan Zhang and Donald W. Miller ). 13 Accumulation of Drugs in Tissues ( Krishnamurthy Venkatesan, Deepa Bisht, and Mohammad Owais ). 14 Salt and Cocrystal Form Selection ( Ann W. Newman, Scott L. Childs, and Brett A. Cowans ). 15 Dissolution ( A.K. Tiwary, Bharti Sapra, and Subheet Jain ). 16 Stability: Physical and Chemical ( Eric M. Gorman, Brian E. Padden, and Eric J. Munson ). 17 Dosage Formulation ( Alexander V. Lyubimov ). 18 Cytochrome P450 Enzymes ( Eugene G. Hrycay and Stelvio M. Bandiera ). 19 Metabolism Kinetics ( Charles W. Locuson and Timothy S. Tracy ). 20 Drug Clearance ( Sree D. Panuganti and Craig K. Svensson ). 21 In Vitro Metabolism in Preclinical Drug Development ( Olavi Pelkonen, Ari Tolonen, Miia Turpeinen, and Jouko Uusitalo ). 22 Utilization of In Vitro Cytochrome P450 Inhibition Data for Projecting Clinical Drug-Drug Interactions ( Jane R. Kenny, Dermot F. McGinnity, Ken Grime, and Robert J. Riley ). 23 In Vivo Metabolism in Preclinical Drug Development ( Sevim Rollas ). 24 In Vitro Evaluation of Metabolic Drug-Drug Interactions: Scientific Concepts and Practical Considerations ( Albert P. Li ). 25 Mechanisms and Consequences of Drug-Drug Interactions ( Dora Farkas, Richard I. Shader, Lisa L. von Moltke, and David J. Greenblatt ). 26 Species Comparison of Metabolism in Microsomes and Hepatocytes ( Niels Krebsfaenger ). 27 Metabolite Profi ling and Structural Identifi cation ( Mehran F. Moghaddam ). 28 Linkage between Toxicology of Drugs and Metabolism ( Ruiwen Zhang and Elizabeth R. Rayburn ). 29 Allometric Scaling ( William L. Hayton and Teh-Min Hu ). 30 Interrelationship between Pharmacokinetics and Metabolism ( James W. Paxton ). 31 Experimental Design Considerations in Pharmacokinetic Studies ( William W. Hope, Vidmantas Petraitis, and Thomas J. Walsh ). 32 Bioavailability and Bioequivalence Studies ( Alexander V. Lyubimov and Ihor Bekersky ). 33 Mass Balance Studies ( Jan H. Beumer, Julie L. Eiseman, and Merrill J. Egorin ). 34 Pharmacodynamics ( Beom Soo Shin, Dhaval Shah, and Joseph P. Balthasar ). 35 Physiologically Based Pharmacokinetic Modeling ( Harvey J. Clewell III, Micaela B. Reddy, Thierry Lave, and Melvin E. Andersen ). 36 Mathematical Modeling as a New Approach for Improving the Effi cacy/Toxicity Profi le of Drugs: The Thrombocytopenia Case Study ( Zvia Agur, Moran Elishmereni, Yuri Kogan, Yuri Kheifetz, Irit Ziv, Meir Shoham, and Vladimir Vainstein ). 37 Regulatory Requirements for INDs/FIH (First in Human) Studies ( Shayne Cox Gad ). 38 Data Analysis ( Jayesh Vora and Pankaj B. Desai ). Index.
Series Title: Pharmaceutical Development Series.
Other Titles: ADME and biopharmaceutical properties
Responsibility: [edited by] Shayne Cox Gad.

Abstract:

This book gives the professional pharmaceutical scientist a basic and comprehensive tool to facilitate the preclinical development process by bringing together an overview of the preclinical process  Read more...

Reviews

Editorial reviews

Publisher Synopsis

"A valuable source of reference and one that I'm sure will get regular use. The diversity of topics should appeal to a variety of pharmaceutical scientists." ( The British Toxicology Newsletter , Read more...

 
User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/214281935> # Preclinical development handbook. ADME and biopharmaceutical properties
    a schema:MediaObject, schema:Book, schema:CreativeWork ;
    library:oclcnum "214281935" ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/1044580578#Place/hoboken_n_j> ; # Hoboken, N.J.
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/nju> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/drug_development> ; # Drug development
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/computer_simulation> ; # Computer Simulation
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/pharmaceutical_preparations_metabolism> ; # Pharmaceutical Preparations--metabolism
    schema:about <http://id.loc.gov/authorities/subjects/sh97007921> ; # Drug development
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/drug_design> ; # Drug Design
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/pharmacokinetics> ; # Pharmacokinetics
    schema:about <http://id.loc.gov/authorities/subjects/sh85100597> ; # Pharmacokinetics
    schema:about <http://dewey.info/class/615.7/e22/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/medical_pharmacology> ; # MEDICAL--Pharmacology
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/computational_biology_methods> ; # Computational Biology--methods
    schema:about <http://experiment.worldcat.org/entity/work/data/1044580578#Topic/models_chemical> ; # Models, Chemical
    schema:alternateName "ADME and biopharmaceutical properties" ;
    schema:bookFormat schema:EBook ;
    schema:contributor <http://viaf.org/viaf/140991175> ; # Wiley InterScience (Online service)
    schema:contributor <http://viaf.org/viaf/112203667> ; # Shayne C. Gad
    schema:copyrightYear "2008" ;
    schema:datePublished "2008" ;
    schema:description "This book gives the professional pharmaceutical scientist a basic and comprehensive tool to facilitate the preclinical development process by bringing together an overview of the preclinical process and a compendium of methods and techniques that need to."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/1044580578> ;
    schema:genre "Handbooks and manuals"@en ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/1044580578#Series/pharmaceutical_development_series> ; # Pharmaceutical Development Series.
    schema:isSimilarTo <http://www.worldcat.org/oclc/176895587> ;
    schema:name "Preclinical development handbook. ADME and biopharmaceutical properties"@en ;
    schema:productID "214281935" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/214281935#PublicationEvent/hoboken_n_j_wiley_interscience_2008> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/1044580578#Agent/wiley_interscience> ; # Wiley-Interscience
    schema:url <http://www.myilibrary.com?id=123741> ;
    schema:url <http://site.ebrary.com/id/10226748> ;
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=225452> ;
    schema:url <http://dx.doi.org/10.1002/9780470249055> ;
    schema:url <http://www.myilibrary.com?id=123741&ref=toc> ;
    schema:url <http://public.eblib.com/choice/publicfullrecord.aspx?p=333797> ;
    schema:workExample <http://worldcat.org/isbn/9780470249024> ;
    schema:workExample <http://worldcat.org/isbn/9781281237415> ;
    schema:workExample <http://dx.doi.org/10.1002/9780470249055> ;
    schema:workExample <http://worldcat.org/isbn/9780470249055> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/214281935> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/1044580578#Agent/wiley_interscience> # Wiley-Interscience
    a bgn:Agent ;
    schema:name "Wiley-Interscience" ;
    .

<http://experiment.worldcat.org/entity/work/data/1044580578#Place/hoboken_n_j> # Hoboken, N.J.
    a schema:Place ;
    schema:name "Hoboken, N.J." ;
    .

<http://experiment.worldcat.org/entity/work/data/1044580578#Series/pharmaceutical_development_series> # Pharmaceutical Development Series.
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/214281935> ; # Preclinical development handbook. ADME and biopharmaceutical properties
    schema:name "Pharmaceutical Development Series." ;
    schema:name "Pharmaceutical Development Series" ;
    .

<http://experiment.worldcat.org/entity/work/data/1044580578#Topic/computational_biology_methods> # Computational Biology--methods
    a schema:Intangible ;
    schema:name "Computational Biology--methods"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1044580578#Topic/computer_simulation> # Computer Simulation
    a schema:Intangible ;
    schema:name "Computer Simulation"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1044580578#Topic/medical_pharmacology> # MEDICAL--Pharmacology
    a schema:Intangible ;
    schema:name "MEDICAL--Pharmacology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1044580578#Topic/pharmaceutical_preparations_metabolism> # Pharmaceutical Preparations--metabolism
    a schema:Intangible ;
    schema:name "Pharmaceutical Preparations--metabolism"@en ;
    .

<http://id.loc.gov/authorities/subjects/sh85100597> # Pharmacokinetics
    a schema:Intangible ;
    schema:name "Pharmacokinetics"@en ;
    .

<http://id.loc.gov/authorities/subjects/sh97007921> # Drug development
    a schema:Intangible ;
    schema:name "Drug development"@en ;
    .

<http://viaf.org/viaf/112203667> # Shayne C. Gad
    a schema:Person ;
    schema:birthDate "1948" ;
    schema:familyName "Gad" ;
    schema:givenName "Shayne C." ;
    schema:name "Shayne C. Gad" ;
    .

<http://viaf.org/viaf/140991175> # Wiley InterScience (Online service)
    a schema:Organization ;
    schema:name "Wiley InterScience (Online service)" ;
    .

<http://worldcat.org/isbn/9780470249024>
    a schema:ProductModel ;
    schema:isbn "0470249021" ;
    schema:isbn "9780470249024" ;
    .

<http://worldcat.org/isbn/9780470249055>
    a schema:ProductModel ;
    schema:isbn "0470249056" ;
    schema:isbn "9780470249055" ;
    .

<http://worldcat.org/isbn/9781281237415>
    a schema:ProductModel ;
    schema:isbn "1281237418" ;
    schema:isbn "9781281237415" ;
    .

<http://www.worldcat.org/oclc/176895587>
    a schema:CreativeWork ;
    rdfs:label "Preclinical development handbook. ADME and biopharmaceutical properties." ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/214281935> ; # Preclinical development handbook. ADME and biopharmaceutical properties
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.