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Preparative enantioselective chromatography

Author: Geoffrey J Cox
Publisher: Ames, Iowa : Blackwell Pub., 2005.
Edition/Format:   Print book : English : 1st edView all editions and formats
Summary:
"Written for chemists, chemical engineers and analytical chemists, Preparative Enantioselective Chromatography demonstrates the considerable utility of the technique in contemporary discovery, development and production scale chemistry. By briefly covering basic preparative chromatography then developing the discussion to cover chiral stationary phases for preparative use, method development and practical  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Geoffrey J Cox
ISBN: 1405118709 9781405118705
OCLC Number: 56051105
Description: xiv, 330 pages : illustrations ; 25 cm
Contents: 1. Chiral chromatography in support of pharmaceutical process research / Christopher J. Welch --
2. Introduction to preparative chromatography / Geoffrey B. Cox --
3. Chiral stationary phases for preparative enantioselective chromatography / Eric Francotte --
4. Method development for preparative enantioselective chromatography / Cristina Suteu --
5. Scaling-up of preparative chromatographic enantiomer separations / Jules Dingenen --
6. Steady-state recycling and its use in chiral separations / Charles M. Grill and Laurence M. Miller --
7. Simulated moving bed and related techniques / Luis S. Pais, Vera G. Mata and Alirio E. Rodrigues --
8. Preparative-scale supercritical fluid chromatography / Manon S. Villeneuve and Luke A. Miller --
9. Equipment for preparative and large size enantioselective chromatography / Henri Colin, Olivier Ludemann-Hombourger and Felicie Denet --
10. Case study in production-scale multicolumn continuous chromatography / Michel Hamende. --
11. Contract manufacturing and outsourcing considerations / Olivier Dapremont.
Responsibility: edited by Geoffrey B Cox.
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Abstract:

"Written for chemists, chemical engineers and analytical chemists, Preparative Enantioselective Chromatography demonstrates the considerable utility of the technique in contemporary discovery, development and production scale chemistry. By briefly covering basic preparative chromatography then developing the discussion to cover chiral stationary phases for preparative use, method development and practical applications, the first part of this book serves as an ideal introduction to the technology for laboratory and pilot plant scale application. The more detailed information presented in the later chapters, on applications in discovery, process development and large scale or production environments, including case studies and equipment selection issues, ensures the book will serve as a sound reference for experienced separation scientists."--BOOK JACKET.

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