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Price indexes for clinical trial research : a feasibility study

ผู้แต่ง: Ernst R Berndt; Iain Cockburn; National Bureau of Economic Research.
สำนักพิมพ์: Cambridge, Mass. : National Bureau of Economic Research, 2013.
ชุด: Working paper series (National Bureau of Economic Research), no. 18918.
ครั้งที่พิมพ์/รูปแบบ:   หนังสืออีเล็กทรอนิกส์ : เอกสาร : ภาษาอังกฤษดูครั้งที่พิมพ์และรูปแบบ
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We estimate hedonic price indexes for clinical trial research, an important component of biomedical R & D, using a large sample of agreements between trial sponsors and clinical investigators obtained from MediData Solutions Worldwide Inc. Nominal prices measured as total grant cost per patient rose by a factor of 4.5 between 1989 and 2011, while the NIH Biomedical R & D Price Index (BRDPI) focused on input costs  อ่านมากขึ้น…
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ขนิดวัสดุ: เอกสาร, ทรัพยากรอินแทอร์เน็ต
ประเภทของเอกสาร: แหล่งข้อมูลอินเทอร์เน็ต, ไฟล์คอมพิวเตอร์
ผู้แต่งทั้งหมด : ผู้แต่งร่วม Ernst R Berndt; Iain Cockburn; National Bureau of Economic Research.
OCLC Number: 835500084
หมายเหตุ: Title from http://www.nber.org/papers/18918 viewed April 4, 2013.
"March 2013."
คำอธิบาย: 1 online resource (35 pages) : illustrations.
ชื่อชุด: Working paper series (National Bureau of Economic Research), no. 18918.
ความรับผิดชอบ: Ernst R. Berndt, Iain M. Cockburn.

บทคัดย่อ:

We estimate hedonic price indexes for clinical trial research, an important component of biomedical R & D, using a large sample of agreements between trial sponsors and clinical investigators obtained from MediData Solutions Worldwide Inc. Nominal prices measured as total grant cost per patient rose by a factor of 4.5 between 1989 and 2011, while the NIH Biomedical R & D Price Index (BRDPI) focused on input costs rose only 2.2-fold. Most of the disparity appears to be attributable to changes in the nature and organization of clinical trials: during this period the average number of patients per site fell substantially while "site work effort" more than doubled. After controlling for these changes in the characteristics of investigator agreements using a variety of methods based on hedonic regressions, we find that the estimated rate of inflation in clinical trials costs tracks the BDRPI very closely. Results from this study suggest that it should be feasible for statistical agencies to develop a producer price index for this type of R & D activity, contributing to broader efforts to develop a deflator for contracted R & D services.

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