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Programming the HPA-axis by early life experience: Mechanisms of stress susceptibility and adaptation.

Author: Rachel Yehuda.; Nikolaos P. Daskalakis.
Publisher: Frontiers Media SA 2015.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related  Read more...
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Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Rachel Yehuda.; Nikolaos P. Daskalakis.
ISBN: 9782889194810 2889194817
OCLC Number: 945783104
Language Note: English.
Description: 1 electronic resource (140 pages)
Other Titles: Directory of open access books.

Abstract:

Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.

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