skip to content
Progress in medicinal chemistry. Vol. 45 Preview this item
ClosePreview this item
Checking...

Progress in medicinal chemistry. Vol. 45

Author: Frank D King; G Lawton
Publisher: Amsterdam ; Oxford : Elsevier, 2007.
Series: Progress in medicinal chemistry, 45
Edition/Format:   eBook : Document : English : 1st edView all editions and formats
Summary:
The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a 'quality lead', where these 'quality leads' come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Progress in medicinal chemistry. Vol. 45.
Amsterdam ; Oxford : Elsevier, 2007
(OCoLC)76851395
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Frank D King; G Lawton
ISBN: 9780080471310 0080471315 0444528083 9780444528087
OCLC Number: 122542942
Description: 1 online resource (1 volume) : illustrations.
Contents: Cover --
Progress in Medicinal Chemistry 45 --
Copyright Page --
Contents --
Preface --
List of Contributors --
Chapter 1. Hit and Lead Identification: Efficient Practices for Drug Discovery --
Introduction --
Hit and Lead Identification Practices --
Lead Identification as Reported for Specific Targets --
Conclusion --
References --
Chapter 2. DPPIV Inhibition: Promising Therapy for the Treatment of Type 2 Diabetes --
Introduction --
Medicinal Chemistry and Preclinical Studies --
Clinical Data for Oral DPPIV Inhibitors --
Conclusions --
Authors Note --
References --
Chapter 3. Recent Progress Toward Nonpeptide Ligands for the Melanocortin-4 Receptor --
Introduction --
Cyclohexylpiperidines as Potent MC4R Agonists --
Cyclohexylpiperazines and Phenylpiperidines --
Phenylpiperazines as MC4R Agonists --
Other Classes of MC4R Agonists --
Compounds Mimicking a-MSH and its Peptide Analogues --
From Agonists to Antagonists --
Small Molecule MC4R Antagonists from Initial Screen Hits --
Other Nonpeptide MC4R Ligands --
Interaction of the MC4R with Ligands --
Medicinal Chemistry --
Conclusion --
References --
Chapter 4. Tuberculosis Chemotherapy: Recent Developments and Future Perspectives --
Introduction --
TB Drug Development Pipeline --
Potential New Drug Targets --
Concluding Comments --
Acknowledgments --
References --
Subject Index --
Author Index (Vols. 1- 45) --
Subject Index (Vols. 1- 45) --
Last Page.
Series Title: Progress in medicinal chemistry, 45
Responsibility: editors, F.D. King and G. Lawton.

Abstract:

What defines a quality lead, where these quality leads come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry. This volume addresses these  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/122542942> # Progress in medicinal chemistry. Vol. 45
    a schema:Book, schema:MediaObject, schema:CreativeWork ;
    library:oclcnum "122542942" ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/2999280323#Place/oxford> ; # Oxford
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/ne> ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/2999280323#Place/amsterdam> ; # Amsterdam
    schema:about <http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_pharmacology> ; # MEDICAL--Pharmacology
    schema:about <http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_pharmacy> ; # MEDICAL--Pharmacy
    schema:about <http://dewey.info/class/615.19/e22/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_nursing_pharmacology> ; # MEDICAL--Nursing--Pharmacology
    schema:about <http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_drug_guides> ; # MEDICAL--Drug Guides
    schema:about <http://id.worldcat.org/fast/1060115> ; # Pharmaceutical chemistry
    schema:bookEdition "1st ed." ;
    schema:bookFormat schema:EBook ;
    schema:contributor <http://experiment.worldcat.org/entity/work/data/2999280323#Person/lawton_g> ; # G. Lawton
    schema:contributor <http://viaf.org/viaf/9953020> ; # Frank D. King
    schema:datePublished "2007" ;
    schema:description "The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a 'quality lead', where these 'quality leads' come from and how one discovers them has been the subject of intense debate within the pharmaceutical industry, relies upon defining those properties that historically have led to successful drug discovery. This volume addresses these questions and specifically discusses diabetes, obesity and tuberculosis. *Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect."@en ;
    schema:description "Cover -- Progress in Medicinal Chemistry 45 -- Copyright Page -- Contents -- Preface -- List of Contributors -- Chapter 1. Hit and Lead Identification: Efficient Practices for Drug Discovery -- Introduction -- Hit and Lead Identification Practices -- Lead Identification as Reported for Specific Targets -- Conclusion -- References -- Chapter 2. DPPIV Inhibition: Promising Therapy for the Treatment of Type 2 Diabetes -- Introduction -- Medicinal Chemistry and Preclinical Studies -- Clinical Data for Oral DPPIV Inhibitors -- Conclusions -- Authors Note -- References -- Chapter 3. Recent Progress Toward Nonpeptide Ligands for the Melanocortin-4 Receptor -- Introduction -- Cyclohexylpiperidines as Potent MC4R Agonists -- Cyclohexylpiperazines and Phenylpiperidines -- Phenylpiperazines as MC4R Agonists -- Other Classes of MC4R Agonists -- Compounds Mimicking a-MSH and its Peptide Analogues -- From Agonists to Antagonists -- Small Molecule MC4R Antagonists from Initial Screen Hits -- Other Nonpeptide MC4R Ligands -- Interaction of the MC4R with Ligands -- Medicinal Chemistry -- Conclusion -- References -- Chapter 4. Tuberculosis Chemotherapy: Recent Developments and Future Perspectives -- Introduction -- TB Drug Development Pipeline -- Potential New Drug Targets -- Concluding Comments -- Acknowledgments -- References -- Subject Index -- Author Index (Vols. 1- 45) -- Subject Index (Vols. 1- 45) -- Last Page."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/2999280323> ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/2999280323#Series/progress_in_medicinal_chemistry> ; # Progress in medicinal chemistry ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/76851395> ;
    schema:name "Progress in medicinal chemistry. Vol. 45"@en ;
    schema:productID "122542942" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/122542942#PublicationEvent/amsterdam_oxford_elsevier_2007> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/2999280323#Agent/elsevier> ; # Elsevier
    schema:url <http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/bookseries/00796468/45> ;
    schema:url <http://site.ebrary.com/id/10166982> ;
    schema:url <http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/book/9780444528087> ;
    schema:url <http://www.sciencedirect.com/science/book/9780444528087> ;
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=187414> ;
    schema:url <http://www.myilibrary.com?id=96265&ref=toc> ;
    schema:url <http://www.myilibrary.com?id=96265> ;
    schema:url <http://www.123library.org/book_details/?id=33396> ;
    schema:url <http://www.sciencedirect.com/science/bookseries/00796468/45> ;
    schema:workExample <http://worldcat.org/isbn/9780444528087> ;
    schema:workExample <http://worldcat.org/isbn/9780080471310> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/122542942> ;
    .


Related Entities

<http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/book/9780444528087>
    rdfs:comment "eBook available for Durham College via Elsevier. Click link to access" ;
    .

<http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/bookseries/00796468/45>
    rdfs:comment "eSeries Volume available for Durham College via Elsevier. Click link to access" ;
    .

<http://experiment.worldcat.org/entity/work/data/2999280323#Person/lawton_g> # G. Lawton
    a schema:Person ;
    schema:familyName "Lawton" ;
    schema:givenName "G." ;
    schema:name "G. Lawton" ;
    .

<http://experiment.worldcat.org/entity/work/data/2999280323#Series/progress_in_medicinal_chemistry> # Progress in medicinal chemistry ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/122542942> ; # Progress in medicinal chemistry. Vol. 45
    schema:name "Progress in medicinal chemistry ;" ;
    .

<http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_drug_guides> # MEDICAL--Drug Guides
    a schema:Intangible ;
    schema:name "MEDICAL--Drug Guides"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_nursing_pharmacology> # MEDICAL--Nursing--Pharmacology
    a schema:Intangible ;
    schema:name "MEDICAL--Nursing--Pharmacology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_pharmacology> # MEDICAL--Pharmacology
    a schema:Intangible ;
    schema:name "MEDICAL--Pharmacology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/2999280323#Topic/medical_pharmacy> # MEDICAL--Pharmacy
    a schema:Intangible ;
    schema:name "MEDICAL--Pharmacy"@en ;
    .

<http://id.worldcat.org/fast/1060115> # Pharmaceutical chemistry
    a schema:Intangible ;
    schema:name "Pharmaceutical chemistry"@en ;
    .

<http://viaf.org/viaf/9953020> # Frank D. King
    a schema:Person ;
    schema:familyName "King" ;
    schema:givenName "Frank D." ;
    schema:name "Frank D. King" ;
    .

<http://worldcat.org/isbn/9780080471310>
    a schema:ProductModel ;
    schema:isbn "0080471315" ;
    schema:isbn "9780080471310" ;
    .

<http://worldcat.org/isbn/9780444528087>
    a schema:ProductModel ;
    schema:isbn "0444528083" ;
    schema:isbn "9780444528087" ;
    .

<http://www.sciencedirect.com/science/bookseries/00796468/45>
    rdfs:comment "URL des Erstveröffentlichers" ;
    .

<http://www.worldcat.org/oclc/76851395>
    a schema:CreativeWork ;
    rdfs:label "Progress in medicinal chemistry. Vol. 45." ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/122542942> ; # Progress in medicinal chemistry. Vol. 45
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.