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Progress in Parkinson research

Author: Franz Hefti; William J Weiner
Publisher: New York : Plenum Press, ©1988.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Database:WorldCat
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Genre/Form: Congresses
Conference papers and proceedings
Additional Physical Format: Online version:
National Parkinson Foundation Symposium on Parkinson Research (1st : 1988 : Miami Beach, Fla.).
Progress in Parkinson research.
New York : Plenum Press, ©1988
(OCoLC)596402652
Online version:
National Parkinson Foundation Symposium on Parkinson Research (1st : 1988 : Miami Beach, Fla.).
Progress in Parkinson research.
New York : Plenum Press, ©1988
(OCoLC)608206047
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Franz Hefti; William J Weiner
ISBN: 0306430967 9780306430961
OCLC Number: 18557987
Notes: Proceedings of the First National Parkinson Foundation Symposium on Parkinson Research, held January 25-26, 1988 in Miami, Florida.
Description: ix, 228 pages, [1] leaf of plates : illustrations ; 26 cm
Contents: 1. The Current Clinical Picture of Parkinson's Disease.- 2. The Neuropathology of Parkinson's Disease.- 3. Anatomical and Pharmacological Comparisons between Dopamine D1 and D2 Receptors in Mammalian CNS.- 4. Architecture of Cholinergic Pre- and Postsynaptic Markers in the Primate Striatum.- 5. Functional Anatomy of Dopamine Receptors.- 6. New Insights into the Regulation of Dopamine Receptor Subtypes and Their Roles in Behavior.- 7. Dopamine Receptors and Signal Transduction.- 8. The Therapeutic Potential of D1 and D2 Dopamine Agonists in Parkinson's Disease.- 9. Isolation and Biochemical Characterization of the D1 and D2 Dopamine Receptors.- 10. MPTP: Twenty Questions.- 11. Search for Environment or Endogenous Neurotoxins Related to MPTP.- 12. MPTP Neurotoxicity and the "Biochemical" Blood-Brain Barrier.- 13. Biochemistry of the Neurotoxic Action of MPTP and What It May Teach Us about Etiology of Idiopathic Parkinsonism.- 14. A Biological Evaluation of Some 2'-Substituted Analogs of MPTP.- 15. Hydrogen Peroxide Production in Dopamine Neurons: Implications for Understanding Parkinson's Disease.- 16. Studies on the Toxicity of MPTP to Dopamine Neurons in Tissue and Cell Cultures.- 17. Toxicity of Structural Analogs of l-Methyl-4-phenyl Pyridinium (MPP+) and Related Compounds on Dopaminergic Neurons in Culture.- 18. Mechanisms of MPP+ Neurotoxicity: Oxyradical and Mitochondrial Inhibition Hypotheses.- 19. Plasticity of Mesencephalic Dopaminergic Neurons.- 20. Trophic Effects of Striatal Proteins on Central Dopaminergic Neurons in Culture.- 21. Age-Related Changes of Dopaminergic Functions.- 22. Adrenal Medulla Transplants in Rodents and Nonhuman Primates: Regenerative Responses in the Host Brain.- 23. Preliminary Evaluation and Report on Human Adrenal Medullary Grafting.- 24. Behavioral Performance Improves after Fetal Substantia Nigra Transplant in Bonnet Monkeys with MPTP Induced Parkinsonism.- 25. Mechanisms of Action of Substantia Nigra and Adrenal Medulla Grafts.- 26. Recent Advances in Dopaminergic Implants.- 27. Reversal of Experimental Parkinsonism in African Green Monkeys Following Fetal Dopamine Neuron Transplantation.- 28. Transplantation of Human Dopaminergic Neurons in Parkinsonism: Experimental Reality and Future Clinical Feasibility.
Responsibility: edited by Franz Hefti and William J. Weiner.
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