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Progress in the reduction, refinement, and replacement of animal experimentation : proceedings of the 3rd World Congress on Alternatives and Animal Use in the Life Sciences, held in Bologna, Italy, from 29 August to 2 September 1999

Author: Michael Balls; A-M van Zeller; M E Halder
Publisher: Amsterdam ; New York : Elsevier Science B.V., 2000.
Series: Developments in animal and veterinary sciences, 31A-31B.
Edition/Format:   Print book : Conference publication : English : 1st edView all editions and formats
Database:WorldCat
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Genre/Form: Congresses
Conference papers and proceedings
Bologna (1999)
Congrès
Additional Physical Format: Online version:
World Congress on Alternatives and Animal Use in the Life Sciences (3rd : 1999 : Bologna, Italy).
Progress in the reduction, refinement, and replacement of animal experimentation.
Amsterdam ; New York : Elsevier Science B.V., 2000
(OCoLC)904220144
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Michael Balls; A-M van Zeller; M E Halder
ISBN: 0444505296 9780444505293
OCLC Number: 44270277
Description: 2 volumes (xxvii, 1795 pages) : illustrations ; 25 cm.
Contents: [V. 1.] Special contributions --
Plenary lectures --
Carcinogenicity testing --
Metabolism-mediated effects --
Genomics, proteomics and gene regulation --
Embryonic stem cells --
Use of reconstituted tissues and co-cultures --
Barrier systems in vitro --
Biocompatibility of materials --
Validation of alternative methods --
Regulatory acceptance of alternative methods --
Predicting toxicity from structure --
Integrated testing and predicting human hazard --
Case studies: eye and skin irritation --
Case studies: skin sensitisation --
Haematotoxicology in vitro --
Experimental design and reduction --
Data analysis and reduction --
Reduction and regulatory testing --
Aspects of cost-benefit analysis --
Antibody production --
[v. 2.] Humane endpoints --
Eliminating vaccine testing in animals --
Validation and acceptance of new methods for biologicals --
Adverse effects: regulation and classification --
Adverse effects: recognition and assessment --
Adverse effects: alleviation and avoidance --
Refinement in experimental design and technique --
Refinement in behavioural research --
Refinement in housing and husbandry: rodents and rabbits --
Refinement in housing and husbandry: other non-rodents --
Use of animals in education and training --
Outreach to scientists on the three Rs --
Outreach to the general public on the three Rs and demonstration of training programmes --
Ethical aspects of transgenesis --
Role of ethical committees --
Animal models --
Point/counterpoint debates --
Workshops --
Closing plenary lectures.
Series Title: Developments in animal and veterinary sciences, 31A-31B.
Responsibility: M. Balls, A-M. van Zeller, and M.E. Halder.

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