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Protein aggregation and fibrillogenesis in cerebral and systemic amyloid disease

Autore: James R Harris
Editore: Dordrecht ; New York : Springer, ©2012.
Serie: Sub-cellular biochemistry, 65.
Edizione/Formato:   eBook : Document : EnglishVedi tutte le edizioni e i formati
Banca dati:WorldCat
Sommario:
This volume of the Subcellular Biochemistry series is the result of the long-standing research interest of the editor in the molecular mechanism underlying Alzheimer's disease and other amyloid diseases, indicated also by the earlier book in the series (Volume 38), devoted to Alzheimer's disease. The broad coverage within the present amyloidogenesis book represents an attempt to collate current knowledge relating to  Per saperne di più…
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Genere/forma: Electronic books
Informazioni aggiuntive sul formato: Print version:
Tipo materiale: Document, Risorsa internet
Tipo documento: Internet Resource, Computer File
Tutti gli autori / Collaboratori: James R Harris
ISBN: 9789400754164 9400754167 9400754159 9789400754157 9781283936118 1283936119
Numero OCLC: 822997147
Note: Includes index.
Descrizione: 1 online resource.
Contenuti: Introduction and technical survey: Protein aggregation and fibrillogenesis --
Fibril formation by short synthetic peptides --
In vitrooligomerization and fibrillogenesis of amyloid-beta peptides --
Tau fibrillogenesis --
Prion protein aggregation and fibrillogenesisin vitro --
Alpha-synuclein aggregation and modulating factors --
Pathological self-aggregation of [beta](2)-microglobulin: A challenge for protein biophysics --
Islet amyloid polypeptide: Aggregation and fibrillogenesisin vitroand its inhibition --
Mechanisms of transthyretin aggregation and toxicity --
Fibrillogenesis of huntingtin and other glutamine containing proteins --
Aggregation and fibrillogenesis of proteins not associated with disease: A few case studies --
Experimental inhibition of peptide fibrillogenesis by synthetic peptides, carbohydrates and drugs --
Experimental inhibition of fibrillogenesis and neurotoxicity by amyloid-beta (abeta) and other disease-related peptides/proteins by plant extracts and herbal compounds --
Alzheimer's disease --
Modeling the polyglutamine aggregation pathway in huntington's disease: From basic studies to clinical applications --
Parkinson's disease --
Human prion diseases: From kuru to variant creutzfeldt-jakob disease --
Animal prion diseases --
[beta](2)-microglobulin amyloidosis --
Systemic AA amyloidosis --
Familial amyloidotic polyneuropathy and transthyretin --
The challenge of systemic immunoglobulin light-chain amyloidosis (AL).
Titolo della serie: Sub-cellular biochemistry, 65.
Responsabilità: J. Robin Harris, editor.
Maggiori informazioni:

Abstract:

This volume of the Subcellular Biochemistry series is the result of the long-standing research interest of the editor in the molecular mechanism underlying Alzheimer's disease and other amyloid diseases, indicated also by the earlier book in the series (Volume 38), devoted to Alzheimer's disease. The broad coverage within the present amyloidogenesis book represents an attempt to collate current knowledge relating to the proteins and peptides involved in most of the known amyloid diseases, together with some amyloid/fibril-forming proteins and peptides that are not involved in diseases. Thus, t.

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