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Protein aggregation and fibrillogenesis in cerebral and systemic amyloid disease

Author: James R Harris
Publisher: Dordrecht : Springer, 2012.
Series: Sub-cellular biochemistry, v. 65.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
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Document Type: Book
All Authors / Contributors: James R Harris
ISBN: 9789400754157 9400754159
OCLC Number: 802321770
Description: xvii, 648 pages : illustrations (some color) ; 24 cm.
Contents: Introduction and technical survey: Protein aggregation and fibrillogenesis --
Fibril formation by short synthetic peptides --
In vitrooligomerization and fibrillogenesis of amyloid-beta peptides --
Tau fibrillogenesis --
Prion protein aggregation and fibrillogenesisin vitro --
Alpha-synuclein aggregation and modulating factors --
Pathological self-aggregation of [beta](2)-microglobulin: A challenge for protein biophysics --
Islet amyloid polypeptide: Aggregation and fibrillogenesisin vitroand its inhibition --
Mechanisms of transthyretin aggregation and toxicity --
Fibrillogenesis of huntingtin and other glutamine containing proteins --
Aggregation and fibrillogenesis of proteins not associated with disease: a few case studies --
Experimental inhibition of peptide fibrillogenesis by synthetic peptides, carbohydrates and drugs --
Experimental inhibition of fibrillogenesis and neurotoxicity by amyloid-beta (abeta) and other disease-related peptides/proteins by plant extracts and herbal compounds --
Alzheimer's disease --
Modeling the polyglutamine aggregation pathway in Huntington's disease: from basic studies to clinical applications --
Parkinson's disease --
Human prion diseases: From kuru to variant Creutzfeldt-jakob disease --
Animal prion diseases --
[beta](2)-Microglobulin amyloidosis --
Systemic AA amyloidosis --
Familial amyloidotic polyneuropathy and transthyretin --
The challenge of systemic immunoglobulin light-chain amyloidosis (AL).
Series Title: Sub-cellular biochemistry, v. 65.
Responsibility: J. Robin Harris, editor.

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