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Protein dynamics : methods and protocols

Author: Dennis R Livesay; Springer Science+Business Media,
Publisher: New York : Humana Press, [2013] ©2014
Series: Methods in molecular biology (Clifton, N.J.), v. 1084; Springer protocols (Series)
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

This book details best-practice recipes covering both experimental and computational techniques, reflecting modern protein research. It features step-by-step detail essential for reproducible results  Read more...

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Genre/Form: Laboratory Manuals
Laboratory manuals
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Dennis R Livesay; Springer Science+Business Media,
ISBN: 1627036571 9781627036573
OCLC Number: 847348527
Description: xiv, 285 pages : illustrations (some color) ; 26 cm.
Contents: Part I: Experimental Methods for Characterizing Protein Dynamics1. Monitoring Side-Chain Dynamics of Proteins Using 2H RelaxationChad M. Petit and Andrew L. Lee 2. CPMG Relaxation Dispersion Rieko Ishima 3. Confocal Single-Molecule FRET for Protein Conformational DynamicsYan-Wen Tan, Jeffrey A. Hanson, Jhih-Wei Chu, and Haw Yang 4. Protein Structural Dynamics Revealed by Site-directed Spin Labeling and Multifrequency EPRYuri E. Nesmelov 5. Probing Backbone Dynamics With Hydrogen/Deuterium Exchange Mass SpectrometryHarsimran Singh and Laura S. Busenlehner 6. Carbon-Deuterium Bonds as Non-perturbative Infrared Probes of Protein Dynamics, Electrostatics, Heterogeneity, and FoldingJoerg Zimmermann and Floyd E. Romesberg Part II: Computational Methods for Characterizing Protein Dynamics7. Balancing Bond, Nonbond and Go-like Terms in Coarse Grain Simulations of Conformational DynamicsRonald D. Hills Jr. 8. Tutorial on Building Markov State Models with MSMBuilder and Coarse-graining them with BACEGregory R. Bowman 9. Analysis of Protein Conformational Transitions Using Elastic Network ModelWenjun Zheng and Mustafa Tekpinar 10. Geometric Simulation of Flexible Motion in ProteinsStephen A. Wells 11. Principal Component Analysis: A Method for Determining the Essential Dynamics of ProteinsCharles C. David and Donald J. Jacobs 12. A Case Study Comparing Quantitative Stability/Flexibility Relationships Across Five Metallo-ss-Lactamases Highlighting Differences within NDM-1Matthew C. Brown, Deeptak Verma, Christian Russell, Donald J. Jacobs, and Dennis R. Livesay 13. Towards Comprehensive Analysis of Protein Family Quantitative Stability/Flexibility Relationships using Homology ModelsDeeptak Verma, Jun-tao Guo, Donald J. Jacobs, and Dennis R. Livesay 14. Using the COREX/BEST Server to Model the Native State EnsembleVincent J. Hilser and Steven T. Whitten 15. Morphing Methods to Visualize Coarse-grained Protein DynamicsDahlia R. Weiss and Patrice Koehl
Series Title: Methods in molecular biology (Clifton, N.J.), v. 1084; Springer protocols (Series)
Responsibility: edited by Dennis R. Livesay, Department of Bioinformatics and Genomic, University of North Carolina at Charlotte, Charlotte, North Carolina, USA.
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