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Protein families : relating protein sequence, structure, and function

Author: Christine A Orengo; Alex Bateman
Publisher: Hoboken, New Jersey : Wiley, [2014]
Series: Wiley series in protein and peptide science.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"This book describes approaches for recognizing and classifying proteins into families of evolutionary related proteins. Reviewing all the major resources for classifying protein families, the book combines descriptions of general philosophies of protein family classification systems with detailed descriptions and examples of selected families found in different biological systems. Scientists in diverse areas of  Read more...
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Additional Physical Format: Online version:
Protein families.
Hoboken, New Jersey : Wiley, [2014]
(DLC) 2013018069
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Christine A Orengo; Alex Bateman
ISBN: 9780470624227 0470624221
OCLC Number: 842307547
Notes: Includes index.
Description: xv, 517 pages, 29 pages of unnumbered plates : illustrations (some color) ; 24 cm.
Contents: Introduction vii Contributors xiii SECTION I. CONCEPTS UNDERLYING PROTEIN FAMILY CLASSIFICATION 1 1 Automated Sequence-Based Approaches for Identifying Domain Families 3 Liisa Holm and Andreas Heger 2 Sequence Classification of Protein Families: Pfam and other Resources 25 Alex Bateman 3 Classifying Proteins into Domain Structure Families 37 Alison Cuff, Alexey Murzin, and Christine Orengo 4 Structural Annotations of Genomes with Superfamily and Gene3D 69 Julian Gough, Corin Yeats, and Christine Orengo 5 Phylogenomic Databases and Orthology Prediction 99 Kimmen Sjolander SECTION II. IN-DEPTH REVIEWS OF PROTEIN FAMILIES 125 6 The Nucleophilic Attack Six-Bladed -Propeller (N6P) Superfamily 127 Michael A. Hicks, Alan E. Barber II, and Patricia C. Babbitt 7 Functional Diversity of the HUP Domain Superfamily 159 Benoit H. Dessailly and Christine Orengo 8 The NAD Binding Domain and the Short-Chain Dehydrogenase/Reductase (SDR) Superfamily 191 Nicholas Furnham, Gemma L. Holliday, and Janet M. Thornton 9 The Globin Family 207 Arthur M. Lesk and Juliette T.J. Lecomte SECTION III. REVIEW OF PROTEIN FAMILIES IN IMPORTANT BIOLOGICAL SYSTEMS 237 10 Functional Adaptation and Plasticity in Cytoskeletal Protein Domains: Lessons from the Erythrocyte Model 239 Anthony J. Baines 11 Unusual Species Distribution and Horizontal Transfer of Peptidases 285 Neil D. Rawlings 12 Deducing Transport Protein Evolution Based on Sequence, Structure, and Function 315 Steven T. Wakabayashi, Maksim A. Shlykov, Ujjwal Kumar, Vamsee S. Reddy, Ankur Malhotra, Erik L. Clarke, Jonathan S. Chen, Rostislav Castillo, Russell De La Mare, Eric I. Sun, and Milton H. Saier 13 Crispr-CAS Systems and CAS Protein Families 341 Kira S. Makarova, Daniel H. Haft, and Eugene V. Koonin 14 Families of Sequence-Specific DNA-Binding Domains in Transcription Factors across the Tree of Life 383 Varodom Charoensawan and Sarah Teichmann 15 Evolution of Eukaryotic Chromatin Proteins and Transcription Factors 421 L. Aravind, Vivek Anantharaman, Saraswathi Abhiman, and Lakshminarayan M. Iyer Index 503
Series Title: Wiley series in protein and peptide science.
Responsibility: edited by Christine A. Orengo, Alex Bateman.

Abstract:

This book describes approaches for recognizing and classifying proteins into families of evolutionary related proteins.  Read more...

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