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Protein trafficking in neurons

Author: Andrew J Bean
Publisher: Amsterdam ; Boston : Elsevier/Academic Press, ©2007.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Protein trafficking in neurons.
Amsterdam ; Boston : Elsevier/Academic Press, ©2007
(DLC) 2006010166
(OCoLC)65341076
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Andrew J Bean
ISBN: 9780123694379 012369437X 9780080465890 0080465897 1280707615 9781280707612
OCLC Number: 162573150
Description: 1 online resource (xv, 448 pages) : illustrations (chiefly illustrations)
Contents: Section I. PROTEIN MOVEMENT. --
Chapter 1. Molecular Mobility in Cells Examined with Optical Methods. --
Chapter 2. The role of Molecular Motors in Axonal Transport. --
Chapter 3. The role of APC complexes and the cytoskeleton in neuronal morphogenesis. --
Section II. SYNAPTIC DEVELOPMENT. --
Chapter 4. Assembly of Synapses in the Vertebrate Central Nervous System. --
Chapter 5. Presynaptic Terminal Differentiation. --
Section III. EXO-/ENDOCYTOSIS. --
Chapter 6. Neuronal Exocytosis. --
Chapter 7. Endocytosis in Neurons. --
Section IV. RECEPTORS. --
Chapter 8. Postsynaptic Machinery for Receptor Trafficking. --
Chapter 9. Synaptic trafficking of AMPA receptors. --
Chapter 10. Subunit-specific NMDA Receptor Trafficking to Synapses. --
Section V. ION CHANNELS/TRANSPORTERS. --
Chapter 11. Membrane Trafficking of Vesicular Transmitter Transporters. --
Chapter 12. Determinants of Voltage-gated Potassium Channel Distribution in Neurons. --
Section VI. PROTEIN TRAFFICKING IN OTHER CELL TYPES. --
Chapter 13. Protein Trafficking in the Exocytic Pathway of Polarized Epithelial Cells. --
Chapter 14. Trafficking in Neuroendocrine Cells. --
Chapter 15. Exocytic Release of Glutamate from Astrocytes: Comparison to Neurons. --
Section VII. PROTEIN TRAFFICKING AND NEURONAL DISEASE. --
Chapter 16. Trafficking Defects in Huntingtons Disease. --
Chapter 17. Neuronal protein trafficking in Alzheimer's disease and Niemann-Pick Type C disease. --
Chapter 18. Trafficking of the Cellular Prion Protein and its Role in Neurodegeneration. Molecular mobility in cells examined with optical methods / M.N. Waxham --
The role of molecular motors in axonal transport / E. Perlson and E.L.F. Holzbaur --
The role of APC complexes and the microtubule cytoskeleton in neuronal morphogenesis / V. Votin, W.J. Nelson, and A.I.M. Barth --
Assembly of synapses in the vertebrate central nervous system / L. Gollan and P. Scheiffele --
Presynaptic terminal differentiation / M. Zhen --
Neuronal exocytosis / S. Sankaranarayanan and T. Ryan --
Endocytosis in neurons / V. Haucke and J. Klingauf --
Postsynaptic machinery for receptor trafficking / K.H. Condon and M.D. Ehlers --
Synaptic trafficking of AMPA receptors / L. Chen and B. Maghsoodi --
Subunit-specific NMDA receptor trafficking to synapses / A. Barria --
Membrane trafficking of vesicular transmitter transporters / R.T. Fremeau, Jr., and R.H. Edwards --
Determinants of voltage-gated potassium channel distribution in neurons / H. Vacher, H. Misonou, and J.S. Trimmer --
Protein trafficking in the exocytic pathway of polarized epithelial cells / C. Yeaman --
Trafficking in neuroendocrine cells / T.F.J. Martin --
Exocytic release of glutamate from astrocytes: comparison to neurons / W. Lee and V. Parpura --
Trafficking defects in Huntington's disease / E. Trushina and C.T. McMurray --
Neuronal protein trafficking in Alzheimer's disease and Niemann-Pick Type C disease / A.M. Cataldo and R.A. Nixon --
Trafficking of the cellular prion protein and its role in neurodegeneration / O. Chakrabarti and R.S. Hegde.
Responsibility: editor, Andrew J. Bean.
More information:

Abstract:

Examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. This book is divided into seven sections that review  Read more...

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