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Proteinases as drug targets

Author: Ben M Dunn; Royal Society of Chemistry (Great Britain)
Publisher: Cambridge, U.K. : Royal Society of Chemistry, [2011], ©2012.
Series: RSC drug discovery series.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book provides vital information on a class of enzymes that have emerged as key drug targets in a number of human diseases, including HIV/AIDS, Hypertension, Cancer, and Alzheimer's disease. There is a gap in information due to the lack of recent international meetings on this subject and, thus, no recent summaries of current research have emerged. The book contains up-to-date information, especially with the  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Proteinases as drug targets.
Cambridge : Royal Society of Chemistry, 2011
(OCoLC)751836291
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Ben M Dunn; Royal Society of Chemistry (Great Britain)
ISBN: 9781849733151 1849733155
OCLC Number: 768415592
Description: 1 online resource (xvi, 275 pages) : illustrations (some color).
Contents: Dipeptidyl peptidases: Substrates and therapeutic targeting in human health and disease; The Metalloproteases Meprin ? and ?: Pathophysiological roles in Inflammation, Cardiovascular Disease, Cancer, and Fibrosis; Glutamate Carboxypeptidase II as a Therapeutic Target; The Role of Proteolytically Inactive Serine Proteases from Sarcoptes scabiei in Complement Evasion; Targeting Dipeptidyl Peptidase-4 (DPP-4) and Fibroblast Activation Protein (FAP) for Diabetes and Cancer Therapy; Discovery of the Cysteine Protease Cathepsin B as a Drug Target for Alzheimer's Disease; Plasmodium falciparum Neutral Aminopeptidases: Development of novel anti-malarials by understanding enzyme structure; Blood-feeding human hookworm proteases; Structural Mechanisms of Inactivation in Proteolytically Inactive Serine Proteases from Sarcoptes scabiei; The Aspartic Proteinases from the Malaria Parasite: Structure and Function of the Plasmepsins
Series Title: RSC drug discovery series.
Responsibility: edited by Ben Dunn.

Abstract:

Describes proteolytic enzymes and their biological function to aid drug discovery by detailing methods of production and assay of the enzymes.  Read more...

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The book thus certainly has the merit to broaden the perspective of readers and will be a good source of new information for those who are already to some degree familiar with research and drug Read more...

 
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