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Proteomic and metabolomic approaches to biomarker discovery

Author: Haleem J Issaq; Timothy Daniel Veenstra
Publisher: Amsterdam : Elsevier Academic Press, [2013]
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are  Read more...
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Document Type: Book
All Authors / Contributors: Haleem J Issaq; Timothy Daniel Veenstra
ISBN: 9780123944467 0123944465
OCLC Number: 822227355
Description: xv, 472 pages : illustrations ; 24 cm
Contents: Biomarker Discovery: Study Design and ExecutionProteomic Technologies for Biomarker DiscoverySample Preparation for ProteomicsSample preparation For metabolomics SOP for serum and plasma Current NMR StrategiesData-independent Mass Spectrometry Extends Detectable Dynamic Range GC/MS LC/MS for: (a) Metabolomics CE/MS for (a) Proteomics (b) Metabolomics Gel electrophoresis The Role of Two-dimensional Gel Electrophoresis in Biomarker DiscoveryAffinity Asp selective Microwave-supported acid proteolysis Fractionation of complex mixturesProtein and Metabolite IdentificationQuantitative proteomics Quantitative analysis of metabolites in biological fluids Statistical & computational analysis Top-down Proteomics for Biomarker DiscoveryA role for protein-protein interaction networks in the identification and characterization of potential biomarkers Protein microarrays Autoantibodies as biomarkersMicroRNAs and Biomarker DiscoveryTissue imaging for biomarker discoveryMS approaches for biomarker verification MS metabolomic data handling for biomarker discoveryBiomarker Validation
Responsibility: edited by Haleem J. Issaq, Timothy D. Veenstra.

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Suitable for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, this title provides the  Read more...

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"The book is primarily aimed at researchers with significant expertise in proteomic or metabolomic technologies with an interest in pursuing biomarker discovery studies. The chapters are well Read more...

 
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