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Protocells : bridging nonliving and living matter

Author: Steen Rasmussen
Publisher: Cambridge, Mass. : MIT Press, ©2009.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells are entities with lifelike properties created from nonliving materials; the book provides in-depth investigations of processes at the interface between living and nonliving matter. Chapters by experts in the field put this state-of-the-art research in the  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Steen Rasmussen
ISBN: 9780262182683 0262182688
OCLC Number: 182913278
Description: xxi, 684 pages, [16] pages of plates : illustrations (some color) ; 24 cm
Contents: The early history of protocells: the search for the recipe of life / Martin M. Hanczyc --
Experimental approaches to fabricating artificial cellular life / David Deamer --
Semisynthetic minimal cells: new advancements and perspectives / Pasquale Stano, Giovanni Murtas, and Pier Luigi Luisi --
A roadmap to protocells / Steen Rasmussen [and others] --
Steps towards a synthetic protocell / Martin M. Hanczyc [and others] --
Assembly of a minimal protocell / Steen Rasmussen [and others] --
Population analysis of liposomes with protein synthesis and a cascading genetic network / Takeshi Sunami [and others] --
Constructive approach to protocells: theory and experiments / Kunihiko Kaneko --
Origin of life and lattice artificial chemistry / Naoaki Ono, Duraid Madina, and Takashi Ikegami --
Models of protocells replication / Richard V. Solé [and others] --
Compositional lipid protocells: reproduction without polynucleotides / Doron Lancet and Barak Shenhav --
Evolutionary microfluidic complementation toward artificial cells / John S. McCaskill --
Self-replication and autocatalysis / Volker Patzke and Günter von Kiedrowski --
Replicator dynamics in protocells / Peter F. Stadler and Bärbel M.R. Stadler --
Peptide nucleic acids as prebiotic and abiotic genetic material / Peter E. Nielsen --
The core of a minimal gene set: insights from natural reduced genomes / Toni Gabaldón [and others] --
Parasitism and protocells: tragedy of the molecular commons / Jeffery J. Tabor [and others] --
Forming the essential template for life: the physics of lipid self-assembly / Ole G. Mouritsen and Ask F. Jakobsen --
Numerical methods for protocell simulations / Yi Jiang [and others] --
Core metabolism as a self-organized system / Eric Smith, Harold J. Morowitz, and Shelley D. Copley --
Energetics, energy flow, and scaling in life / William H. Woodruff --
Gánti's Chemoton Model and life criteria / James Griesemer and Eörs Szathmáry --
Viral individuality and limitations of the life concept / David C. Krakauer and Paolo Zanotto --
Nonlinear chemical dynamics and the origin of life: the inorganic-physical chemist point of view / Jerzy Maselko and Maciej Maselko --
Early ancestors of existing cells / Andrew Pohorille --
Prebiotic chemistry, the primordial replicator, and modern protocells / Henderson James Cleaves II --
Cell-like entities: scientific challenges and future applications / John M. Frazier [and others] --
Social and ethical issues concerning protocells / Mark A. Bedau and Emily C. Parke.
Responsibility: edited by Steen Rasmussen [and others].
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Abstract:

The first comprehensive general resource on state-of-the-art protocell research, describing current approaches to making new forms of life from scratch in the laboratory.  Read more...

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"To create life from scratch is the ultimate goal of origin of life research and one of the great scientific challenges of 21st century. A program to synthesize wet artificial life was initiated by a Read more...

 
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    schema:reviewBody ""Protocells offers a comprehensive resource on current attempts to create simple forms of life from scratch in the laboratory. These minimal versions of cells are entities with lifelike properties created from nonliving materials; the book provides in-depth investigations of processes at the interface between living and nonliving matter. Chapters by experts in the field put this state-of-the-art research in the context of theory, laboratory work, and computer simulations on the components and properties of protocells. The book also provides perspectives on research in related areas and such broader societal issues as commercial applications and ethical considerations." "The book covers all major scientific approaches to creating minimal life, both in the laboratory and in simulation. It emphasizes the bottom-up view of physicists, chemists, and material scientists but also includes the molecular biologists' top-down approach and the origin-of-life perspective. The capacity to engineer living technology could have an enormous socioeconomic impact and could bring both good and ill."--Jacket." ;
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