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Pseudo-peptides in drug development

Author: Peter E Nielsen; Wiley InterScience (Online service)
Publisher: Weinheim : Wiley-VCH ; Chichester : John Wiley, 2003.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

Peptides are among the most versatile bioactive molecules, yet the do not make good drugs. To overcome this problem, pseudo-peptides have been developed. This work is devoted to the topic and draws  Read more...

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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Peter E Nielsen; Wiley InterScience (Online service)
ISBN: 3527306331 9783527306336 9783527601905 3527601902
OCLC Number: 65187419
Notes: Title from title screen (viewed on Mar 23, 2006).
Description: 200 pages
Details: Mode of access: World Wide Web.
Contents: Preface.List of Contributors.1. Versatile Oligo(N-Substituted) Glycines: The Many Roles of Peptoids in Drug Discovery (J. Patch, et al.). 2. s-Peptides, y-Peptides and Isosteric Backbones: New Scaffolds with Controlled Shapes for Mimicking Protein Secondary Structure Elements (G. Guichard).3. Regulation of Gene Expression with Pyrrole-Imidazole Polyamides (P. Dervan, et al.).4. Peptide Nucleic Acid (PNA): A Pseudo-peptide with DNA-like Properties (P. Nielsen, et al.). 5. a-Helical Peptide Nucleic Acids (aPNAs) (P. Garner, et al.). 6. DNA and RNA-cleaving Pseudo-peptides (A. Scarso & P. Scarso).Subject Index.
Responsibility: Peter E. Neilsen.

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"...thoughtfully compiled and well-presented. Researchers working in these specific areas will want to own a copy of this book..." (Journal of the American Chemical Society, February 23, 2005) Read more...

 
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