skip to content
RAS and RAF signaling in melanoma : biology and therapies Preview this item
ClosePreview this item
Checking...

RAS and RAF signaling in melanoma : biology and therapies

Author: Richard Marais
Publisher: London : Henry Stewart Talks, 2010.
Series: Henry Stewart talks., Biomedical & life sciences collection., Protein phosphorylation.
Edition/Format:   eVideo : Clipart/images/graphics : EnglishView all editions and formats
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

 

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Material Type: Clipart/images/graphics, Internet resource, Videorecording
Document Type: Internet Resource, Computer File, Visual material
All Authors / Contributors: Richard Marais
OCLC Number: 720056198
Notes: Animated audio-visual presentation with synchronized narration.
Title from title frames.
Description: 1 streaming video file (37 min.) : digital, mono, SWF file, sound, color.
Details: Mode of access: World Wide Web.; System requirements: Operating System: PC Windows 2000+, Mac OSX+ 3.2. Browser Compatibility: IE6+, Firefox 2+, Opera 9+, Safari 2+ 3.3. Browser settings: enable JavaScript, enable popups from the Henry Stewart Talks site. 3.4. Required Browser Plugins & Viewers: Adobe (Macromedia) Flash Player 7+, Adobe Acrobat Reader 6.0+.
Contents: Melanoma --
BRAF and RAS mutated in approximately 70% of cases --
Mouse models of melanoma --
Oncogenic BRAF can be a founder mutation in melanoma --
Mouse models replicate human disease --
BRAF inhibitors induce paradoxical activation of CRAF and drive pathway activation --
Kinase-dead BRAF mimics this and potentiates RAS ooncogenesis --
BRAF inhibitors induce excellent responses in patients, but may induce mechanism-based side effects through CRAF.
Series Title: Henry Stewart talks., Biomedical & life sciences collection., Protein phosphorylation.
Other Titles: RAS and RAF signalling in melanoma
Responsibility: Richard Marais.
More information:

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/720056198> # RAS and RAF signaling in melanoma : biology and therapies
    a schema:CreativeWork, schema:VideoObject, schema:Movie ;
   library:oclcnum "720056198" ;
   library:placeOfPublication <http://dbpedia.org/resource/London> ; # London
   library:placeOfPublication <http://id.loc.gov/vocabulary/countries/enk> ;
   rdfs:comment "Unknown 'gen' value: cig" ;
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/signal_transduction> ; # Signal Transduction
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/neoplasm_proteins> ; # Neoplasm Proteins
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/melanoma_treatment> ; # Melanoma--Treatment
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/proto_oncogene_proteins_b_raf> ; # Proto-Oncogene Proteins B-raf
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/melanoma_therapy> ; # Melanoma--therapy
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/ras_oncogenes> ; # Ras oncogenes
   schema:about <http://experiment.worldcat.org/entity/work/data/791200812#Topic/genes_ras> ; # Genes, ras
   schema:alternateName "RAS and RAF signalling in melanoma" ;
   schema:creator <http://experiment.worldcat.org/entity/work/data/791200812#Person/marais_richard> ; # Richard Marais
   schema:datePublished "2010" ;
   schema:description "Melanoma -- BRAF and RAS mutated in approximately 70% of cases -- Mouse models of melanoma -- Oncogenic BRAF can be a founder mutation in melanoma -- Mouse models replicate human disease -- BRAF inhibitors induce paradoxical activation of CRAF and drive pathway activation -- Kinase-dead BRAF mimics this and potentiates RAS ooncogenesis -- BRAF inhibitors induce excellent responses in patients, but may induce mechanism-based side effects through CRAF."@en ;
   schema:exampleOfWork <http://worldcat.org/entity/work/id/791200812> ;
   schema:inLanguage "en" ;
   schema:isPartOf <http://experiment.worldcat.org/entity/work/data/791200812#Series/protein_phosphorylation> ; # Protein phosphorylation
   schema:isPartOf <http://experiment.worldcat.org/entity/work/data/791200812#Series/henry_stewart_talks> ; # Henry Stewart talks.
   schema:name "RAS and RAF signaling in melanoma : biology and therapies"@en ;
   schema:productID "720056198" ;
   schema:publication <http://www.worldcat.org/title/-/oclc/720056198#PublicationEvent/london_henry_stewart_talks_2010> ;
   schema:publisher <http://experiment.worldcat.org/entity/work/data/791200812#Agent/henry_stewart_talks> ; # Henry Stewart Talks
   schema:url <http://hstalks.com/lib.php?t=HST116.2684&c=252> ;
   schema:url <https://hstalks.com/bs/1896/> ;
   schema:url <http://hstalks.com/lib.php?t=HST116.2684_1_2&c=252> ;
   wdrs:describedby <http://www.worldcat.org/title/-/oclc/720056198> ;
    .


Related Entities

<http://dbpedia.org/resource/London> # London
    a schema:Place ;
   schema:name "London" ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Agent/henry_stewart_talks> # Henry Stewart Talks
    a bgn:Agent ;
   schema:name "Henry Stewart Talks" ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Person/marais_richard> # Richard Marais
    a schema:Person ;
   schema:familyName "Marais" ;
   schema:givenName "Richard" ;
   schema:name "Richard Marais" ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Series/henry_stewart_talks> # Henry Stewart talks.
    a bgn:PublicationSeries ;
   schema:hasPart <http://www.worldcat.org/oclc/720056198> ; # RAS and RAF signaling in melanoma : biology and therapies
   schema:name "Henry Stewart talks." ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Series/protein_phosphorylation> # Protein phosphorylation
    a bgn:PublicationSeries ;
   schema:hasPart <http://www.worldcat.org/oclc/720056198> ; # RAS and RAF signaling in melanoma : biology and therapies
   schema:name "Protein phosphorylation" ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Topic/melanoma_treatment> # Melanoma--Treatment
    a schema:Intangible ;
   schema:name "Melanoma--Treatment"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Topic/proto_oncogene_proteins_b_raf> # Proto-Oncogene Proteins B-raf
    a schema:Intangible ;
   schema:name "Proto-Oncogene Proteins B-raf"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/791200812#Topic/signal_transduction> # Signal Transduction
    a schema:Intangible ;
   schema:name "Signal Transduction"@en ;
    .

<http://hstalks.com/lib.php?t=HST116.2684_1_2&c=252>
   rdfs:comment "e-Video Henry Stewart Talks Biomedical (play video)" ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.