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Recent advances in proteomics research

Author: Ming D Li
Publisher: New York : Nova Science Publishers, 2014.
Series: Protein Biochemistry, Synthesis, Structure and Cellular Functions.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The primary objective of this book is to provide updated knowledge of recent advances in proteomics research in various fields. The topics covered include, but are not limited to, proteomic analysis for microbiomes, specific cell types from heterogeneous tissues, body fluids, mitochondria, and environmental toxicology. Almost all proteomics techniques currently used in research have been reviewed in at least one  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Recent advances in proteomics research
(OCoLC)866584486
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Ming D Li
ISBN: 9781629482217 1629482218
OCLC Number: 869460199
Description: 1 online resource.
Contents: RECENT ADVANCES IN PROTEOMICS RESEARCH; RECENT ADVANCES IN PROTEOMICS RESEARCH; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter 1 Protein Level Analysis from Specific Cell Types in Heterogeneous Tissue; Abstract; Introduction; Laser Capture Microdissection and the Proteome; Immuno-LCM; Immuno-PCR; Biobarcoding and Nanoparticles; Aptamers; Mass Spectrometry; Discussion; Acknowledgments; References; Chapter 2 Neuroproteomics and Its Applicationin Drug Addiction Study; Abstract; 1. Introduction; 2. Proteome Dynamics and Complexity in Substance Abuse Research. 3. Proteomic Techniques4. Bioinformatics; 5. Challenges and Limitations of Neuroproteomics Approaches; 6. Protein arrays; 7. Recent Applications of Neuroproteomics in Research on Nicotine and Other Substances of Abuse; 8. Proteomics Provides Insights into Mechanisms Underlying Drug Addiction; Summary and Conclusion; Acknowledgments; References; Chapter 3 Current Proteomics Methods for Analysing the Human Microbiome; Abstract; Introduction; Proteomics in Bacterial Research; Proteomic Tools; Protein Identification; The Limits of Proteomics; Future Directions; References. Chapter 4 Analysis of Pleural Fluid: The Path Travelled with Proteomic GuidanceAbstract; 1. Introduction; 2. Why Proteomics? --
Limitations of Microscopic Analysis of Pleural Fluid; 3. Pre-Analytic and Intra-Analytical Variables of the Pleural Fluid Proteome; 4. The Pleural Fluid Proteome is a Great Place to Search for Cancer Biomarkers --
Why?; 5. Early Efforts --
Challenges and Promising Discoveries; 6. Cancer Specific Discovery Proteomic Efforts -A Gold Mine of Information; 7. Secretome Analysis with Pleural Effusion Proteome Study --
A Promising Path. 8. Recent Studies with Mudpit and Other Methods- Many New Biomarker CandidatesConclusion; References; Chapter 5 Application of Quantitative Proteomics to Disease Diagnosis and Prognosis Using Stable Isotope Dimethyl Labeling Coupled with Shotgun Proteomics Strategy and Multiple Reaction Monitoring; Abstract; 1. Introduction; 2. Proteomic Methodologies and Platforms; 3. Proteomics Study on Three Exemplar Clinical Cases; Conclusion; Acknowledgments; References; Chapter 6 Mitochondria Protein Profilingin Striated Muscle: Insights into Pathophysiological Conditions; Abstract; 1. Introduction. 2. Mitochondrial Proteome Characterization in Striated Muscle3. Mitochondrial Proteome Plasticity in Pathophysiological Conditions; 4. Future Perspectives; Acknowledgments; References; Chapter 7 Structural Mass Spectrometry of Halophilic Proteasomal Nanomachines Using Chemical Cross-Linking; Abstract; Introduction; Structural Mass Spectrometry; General Principle and Strategies of CXMS; Characteristics of Cross-Linkers; Bioinformatics in Cross-Link Identification; CXMS and Comparative Modeling; Investigation of Multiprotein Complexes by Methods of Structural Proteomics.
Series Title: Protein Biochemistry, Synthesis, Structure and Cellular Functions.
Responsibility: edited by Ming D. Li.

Abstract:

The primary objective of this book is to provide updated knowledge of recent advances in proteomics research in various fields. The topics covered include, but are not limited to, proteomic analysis for microbiomes, specific cell types from heterogeneous tissues, body fluids, mitochondria, and environmental toxicology. Almost all proteomics techniques currently used in research have been reviewed in at least one chapter, including traditional one- or two-dimensional gel-based, gel-free shotgun, label-based or label-free quantitative, and array-based methods. In addition, although they are not.

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