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Reducing, refining and replacing the use of animals in toxicity testing

Author: Dave Allen; Mike D Waters
Publisher: Cambridge : Royal Society of Chemistry, [2014] ©2014
Series: Issues in toxicology.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

This thought-provoking book describes the ever-expanding "toolbox" of methods now available to reduce, refine, or replace animal usage in toxicity testing.

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Genre/Form: Electronic books
Additional Physical Format: Print version:
Reducing, refining and replacing the use of animals in toxicity testing.
Cambridge : Royal Society of Chemistry, 2014
vii, 369 pages : color illustrations.
(OCoLC)862306945
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Dave Allen; Mike D Waters
ISBN: 9781849737920 1849737924 1849736529 9781849736527
OCLC Number: 868917078
Description: 1 online resource (385 pages) : color illustrations.
Contents: Introduction; The 3R's in Toxicity Testing - From Russell and Birch to 21st Century Toxicology; Regulatory Safety Testing - National and International Requirements; Efforts Towards International Harmonization of Acceptable Alternatives; Refinement Alternatives - Minimizing Pain and Distress in In Vivo Toxicity Testing; In Vitro Toxicity Testing - The Basics; Using Stem Cells in Toxicity Testing; Using Computers Instead of Cells - In Silico Approaches to Toxicity Testing; Acute Safety Testing; Acute Systemic Toxicity - Oral, Dermal, and Inhalation Exposures; Dermal Corrosivity and Irritation Testing; Ocular Corrosivity and Irritation Testing; Skin Sensitization Testing; Integrated Approaches to Acute Safety Testing; Endocrine Disruptors; In Vitro Receptor Binding Assays; In Vitro Receptor Transactivation Assays; Non-mamalian Approaches to Identifying Endocrine Active Substances; Subchronic and Chronic Toxicity Testing; Carcinogenicity - Genetic Toxicity Testing and Beyond; Reproductive and Developmental Toxicity Testing; Immunotoxicity Testing; Application of New Technologies; High Throughput Approaches to Toxicity Testing; Nanotechnology - New Challenges in Toxicity Testing
Series Title: Issues in toxicology.
Responsibility: edited by Dave Allen and Mike D Waters.

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