pular para conteúdo
Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus.
FecharVer prévia deste item
Checando...

Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus.

Autor: IA Parshikov Afiliação: Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.JP FreemanLay JO JrRD BegerAJ WilliamsTodos os autores
Edição/Formato Artigo Artigo : Inglês
Publicação:FEMS microbiology letters, 1999 Aug 01; 177(1): 131-5
Base de Dados:De MEDLINE®/PubMed®, uma base de dados da Biblioteca Nacional de Medicina dos EUA.
Outras Bases de Dados: British Library SerialsArticleFirst
Resumo:
A strain of the saprobic fungus Mucor ramannianus, isolated from a forest, was used to demonstrate the potential for ciprofloxacin biotransformation by zygomycetes in the environment. The fungus carried out the regioselective N-acetylation of ciprofloxacin to a single product, which was purified from culture extracts by high-performance liquid chromatography. The metabolite was identified by mass and nuclear  Ler mais...
Classificação:

(ainda não classificado) 0 com críticas - Seja o primeiro.

 

&AllPage.SpinnerRetrieving;

Encontrar uma cópia na biblioteca

&AllPage.SpinnerRetrieving; Encontrando bibliotecas que possuem este item...

Detalhes

Tipo de Documento: Artigo
Todos os Autores / Contribuintes: IA Parshikov Afiliação: Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA.; JP Freeman; Lay JO Jr; RD Beger; AJ Williams; JB Sutherland
ISSN:0378-1097
Nota do Idioma: English
Idenficador Único: 121324418
Prêmios:

Resumo:

A strain of the saprobic fungus Mucor ramannianus, isolated from a forest, was used to demonstrate the potential for ciprofloxacin biotransformation by zygomycetes in the environment. The fungus carried out the regioselective N-acetylation of ciprofloxacin to a single product, which was purified from culture extracts by high-performance liquid chromatography. The metabolite was identified by mass and nuclear magnetic resonance spectrometry as 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-acetyl-1-piperazinyl)-3- quinolinecarboxylic acid.

Críticas

Críticas contribuídas por usuários
Recuperando críticas GoodReas...
Recuperando comentários DOGObooks

Etiquetas

Seja o primeiro.
Confirmar esta solicitação

Você já pode ter solicitado este item. Por favor, selecione Ok se gostaria de proceder com esta solicitação de qualquer forma.

Dados Ligados


Primary Entity

<http://www.worldcat.org/oclc/121324418> # Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus.
    a schema:Article, schema:CreativeWork ;
    library:oclcnum "121324418" ;
    rdfs:comment "949 $l Research Support, U.S. Gov't, Non-P.H.S." ;
    rdfs:comment "949 $l Research Support, U.S. Gov't, P.H.S." ;
    rdfs:comment "949 $l Journal Article" ;
    schema:contributor <http://experiment.worldcat.org/entity/work/data/80148723#Person/freeman_jp> ; # Freeman JP
    schema:contributor <http://experiment.worldcat.org/entity/work/data/80148723#Person/lay_jo_jr> ; # Lay JO Jr
    schema:contributor <http://experiment.worldcat.org/entity/work/data/80148723#Person/williams_aj> ; # Williams AJ
    schema:contributor <http://experiment.worldcat.org/entity/work/data/80148723#Person/beger_rd> ; # Beger RD
    schema:contributor <http://experiment.worldcat.org/entity/work/data/80148723#Person/sutherland_jb> ; # Sutherland JB
    schema:creator <http://experiment.worldcat.org/entity/work/data/80148723#Person/parshikov_ia> ; # Parshikov IA
    schema:description "A strain of the saprobic fungus Mucor ramannianus, isolated from a forest, was used to demonstrate the potential for ciprofloxacin biotransformation by zygomycetes in the environment. The fungus carried out the regioselective N-acetylation of ciprofloxacin to a single product, which was purified from culture extracts by high-performance liquid chromatography. The metabolite was identified by mass and nuclear magnetic resonance spectrometry as 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-acetyl-1-piperazinyl)-3- quinolinecarboxylic acid." ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/80148723> ;
    schema:isPartOf <http://worldcat.org/issn/0378-1097#177_1> ;
    schema:name "Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus." ;
    schema:pageStart "131" ;
    schema:productID "121324418" ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/121324418> ;
    .


Related Entities

<http://worldcat.org/issn/0378-1097>
    a schema:Periodical ;
    rdfs:label "FEMS microbiology letters" ;
    schema:issn "0378-1097" ;
    .

<http://www.worldcat.org/title/-/oclc/121324418>
    a genont:InformationResource, genont:ContentTypeGenericResource ;
    schema:about <http://www.worldcat.org/oclc/121324418> ; # Regioselective transformation of ciprofloxacin to N-acetylciprofloxacin by the fungus Mucor ramannianus.
    schema:dateModified "2016-06-15" ;
    void:inDataset <http://purl.oclc.org/dataset/medline> ;
    .


Content-negotiable representations

Close Window

Por favor, conecte-se ao WorldCat 

Não tem uma conta? Você pode facilmente criar uma conta gratuita.