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Regulation of Differentiation in Mammalian Nerve Cells

Author: Kedar N Prasad
Publisher: Boston, MA : Springer US, 1995.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

With the use of clonal lines of neuronal cells and hybrid neural cells (neural cells x nonneural cells), many new concepts have emerged con- cerning the regulation of differentiated functions, the  Read more...

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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Kedar N Prasad
ISBN: 9781468481129 1468481126 9781468481143 1468481142
OCLC Number: 840289689
Description: 1 online resource
Contents: 1. Definition and Methodologies --
Definition of Differentiation --
Criteria of Differentiation of Nerve Cells --
Available Models with Which to Study the Problem of Differentiation --
Conclusion --
References --
2. Neutral Induction --
Neural Induction --
Current Status of Induction Mechanisms of Neural Tissue --
References --
3. Role of Cyclic Nucleotides in Regulation of Differentiation of Nerve Cells --
Experimental Models --
Methods of Evaluating Changes in Genetic and Structural Expressions --
Modification of Gene Expression and Morphology Unique to Cell Culture Condition and Experimental Models --
Regulation of Morphological Differentiation --
Polyunsaturated Fatty Acid Metabolism during Differentiation --
Modification of Gene Expression by cAMP --
Effect of Vitamin C --
Can Differentiated Cells Act As a Strong Antigen? --
Suggestion of a New Approach for the Treatment of Neuroblastomas --
Clinical Trial of Differentiating Agents --
Conclusion --
References --
4. Role of Agents Other than cAMP in the Regulation of Differentiation of Nerve Cells --
Nerve Growth Factor --
Effect of Thyroid Hormone --
Effect of Growth Hormone --
Cell-Cycle Changes during Neuronal Differentiation --
Role of Cell Interactions in the Regulation of Cholinergic Enzymes during Neural Differentiation --
Regulation of Neural Tube Closure --
Effect of Nonneural Elements --
Effect of Heavy Water (D2O) --
Effect of Serum-Free Medium and X Irradiation --
Effect of 6-Thioguanine, Cytosine Arabinoside, Methotrexate, and 5-Bromodeoxyuridine --
Effect of Glial Extract --
Effect of Hypertonic Medium --
Effect of Collagen --
Effect of Liposome --
Conclusion --
References --
5. Parent and Hybrid Neuroblastoma Cells in Culture as a Model System for Neuronal Function --
Hybrid Cells (Mouse Neuroblastoma Cells × Mouse Fibroblast Cells) --
Hybrid Cells (Mouse Neuroblastoma Cells × Rat Glioma Cells) --
Hybrid Cells (Mouse Neuroblastoma Cells × Mouse Sympathetic Ganglion Cells) --
Hybrid Cells in the Study of Narcotic Addiction --
Uptake Study Using Parent Neuroblastoma Clones --
Intracellular Biogenic Amines --
Transport of Glucose --
Metabolism of Glycogen --
Distribution of Free Nucleotides --
Distribution of Free Amino Acids --
Phospholipid Metabolism --
Immunology of Neuroblastoma Cells --
Effect of Quinazoline Antifolates --
Effect of Nonneural Cells on the Expression of Neuronal Functions --
Conclusion --
References --
6. Some Aspects of Development of Nervous Tissue --
Morphogenesis --
Neuronal Interaction --
Cell Recognition --
Cell Adhesion --
Neuronal Death --
Functions of Cholinergic Input --
Neuronal Plasticity --
References.
Responsibility: by Kedar N. Prasad.

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