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Renaissance of sickle cell disease research in the genome era

Author: Betty Pace
Publisher: London : Imperial College Press ; Hackensack, NJ : Distributed by World Scientific Pub., ©2007.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

The Human Genome Project has spawned a Renaissance of research faced with the expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a  Read more...

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Document Type: Book
All Authors / Contributors: Betty Pace
ISBN: 9781860946455 1860946453
OCLC Number: 122932799
Description: xxxv, 357 pages : illustrations ; 27 cm
Contents: Sickle cell disease: demystifying the beginnings / Clarice Reid and Griffin Rodgers --
Sponsorship of Sickle Cell disease research by the National Institues of health: a brief history and projections for the future / Gregory L. Evans and David G. Badman --
The human genome project / Betty S. Pace --
Sickle Cell disease: a phenotypic patchwork / Kim Smith-Whitley and Betty S. Pace --
Preventive care and advances in the treatment of Sickle Cell disease / Charles T. Quinn and George R. Buchanan --
Sickle cell disease in adults / Johnson Haynes, Jr. and Ardie Pack-Mabien --
Pain in Sickle Cell disease: a multidimensional construct / Lennette J. Benjamin and Richard Payne --
Transfusion therapy in Sickle Cell disease / Carolyn Hoppe, Robert Adams and Elliot Vichinsky --
Hemoglobin S polymerization, just the beginning / Frank A. Ferrone --
Damage to the red blood cell membrane in Sickle Cell disease / Steven R. Goodman and Clinton Joiner --
Fetal hemoglobin for what ails Sickle hemoglobin / Solomon F. Ofori-Acquah and Betty S. Pace --
Genetic modulation of Sickle Cell disease / Martin H. Steinberg and Swee Lay Thein --
Molecular framework of hemoglobin switching / Steven Fiering --
Dynamic nucleoprotein structure of the B-Globin locus: establishing a rational molecular basis for therapeutic modulation of hemoglobin switching / Emery Bresnick, Hogune Im, Kirby D. Johnson, Meghan E. Boyer and Jeffrey A. Grass --
Vertebrate models for Sickle Cell disease research / Barry H. Paw, Seong-Kyu Choe, Flavia C. Costa, Shirin V. Sundar and Kenneth Peterson --
Stem cell biology / Wei Li and Alan W. Flake --
Bone marrow transplantation / Robert I. Raphael and Mark C. Walters --
Genetically engineered cures: gene therapy for Sickle Cell disease / Punam Malik and Philippe Leboulch --
Sickle Cell disease: the past, present and future social and ethical dilemmas / Vence L. Bonham, Jr., Carlton Haywood, Jr. and Vanessa Northington Gamble --
It takes a village to cure Sickle Cell disease / Rosie Peterson and Denise Davis-Maye --
Beyond national borders: a global perspective on advances in Sickle Cell disease research and management, and new challenges in the genome era / Solomon F. Ofori-Acquah and Kwaku Ohere-Frempong.
Responsibility: Betty Pace.

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