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Research Priorities for Helminth Infections : Technical Report of the TDR Disease Reference Group on Helminth Infections.

Author: World Health Organization
Publisher: Geneva : World Health Organization, 2012.
Series: Technical Report Series.
Edition/Format:   eBook : Document : English
Summary:
Over a billion people in sub-Saharan Africa Asia andthe Americas are infected with one or more helminthspecies causing morbidity that helps maintain the viciouscycle of poverty decreased productivity and inadequatesocioeconomic development. This report presents an evaluation of current research andchallenges in controlling the helminthiases of public healthimportance including onchocerciasis lymphatic filariasis  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Organization, World Health.
Research Priorities for Helminth Infections : Technical Report of the TDR Disease Reference Group on Helminth Infections.
Geneva : World Health Organization, ©2012
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: World Health Organization
ISBN: 9789240688612 9240688617
OCLC Number: 830162438
Notes: 4.8.4 Infection and disease mapping.
Description: 1 online resource (197 pages).
Contents: Cover; Contents; The TDR Disease Reference Group on Helminth Infections; Acronyms and abbreviations; List of species; Executive summary; 1. Introduction; 1.1 The problem of helminthiases; 1.2 Human helminthiases, populations at risk and resulting diseases; 1.3 Group membership; 1.4 Host country; 1.5 Think Tank members; 2. Methodology and prioritization; 2.1 Identification of the helminth infections to be considered; 2.2 Identification of the research gaps to be considered; 2.3 The first DRG4 meeting; 2.4 Prioritization of themes; 2.4.1 Underlying values; 2.4.2 Criteria for ranking. 2.5 The second DRG4 meeting2.6 Ranking of priority research areas by experts in DRG4; 2.7 Stakeholders consultation meetings and other external contributions; 2.7.1 First stakeholders' consultation; 2.7.2 Second stakeholders' consultation; 2.8 Publication of the DRG4 report; 3. Overview of trends and driving forces of persistent, emerging and re-emerging helminth infections and the consequent research and control challenges; 3.1 Parasite population biology and human host sociological factors; 3.2 Chemotherapeutic factors. 3.3 Factors associated with current ability to diagnose helminth infections in individuals, communities and larger spatial scales3.4 Factors associated with the environmental and social ecology of human helminthiases; 3.5 Factors associated with research gaps in basic helminth biology; 4. Overview of significant recent advances for the control and elimination of helminth infections and deeper analysis of control challenges and research issues for helminth diseases; 4.1 Advances in interventions and their monitoring and evaluation; 4.2 Analysis of the tools for control interventions. 4.2.1 Anthelmintic pharmaceuticals and their modalities of delivery4.2.2 Efficacy of anthelmintics; 4.2.3 Anthelmintic resistance; 4.2.4 Combinations of anthelmintics; 4.2.5 Vector control; 4.2.6 Vaccines; 4.3 Advances in tools for diagnosis of infection and surveillance of interventions; 4.4 Analysis of the tools for diagnosis, monitoring and evaluation, and surveillance and their challenges; 4.4.1 Diagnostics for filariases; 4.4.2 Diagnostics for soil-transmitted helminthiases. 4.4.3 Diagnostics for schistosomiasis (including infections by Schistosoma mansoni, S. haematobium and S. japonicum)4.4.4 Diagnostics for taeniasis (Taenia solium/cysticercosis); 4.5 Issues related to bringing new diagnostics to market; 4.6 Advances in mathematical modelling of helminth infections; 4.7 Advances in the understanding of pathology and assessment of morbidity; 4.8 Analysis of the challenges for epidemiological data and mathematical models; 4.8.1 Transmission thresholds; 4.8.2 Parasite population biology factors; 4.8.3 Co-infections, multiple populations, and niche-shifts.
Series Title: Technical Report Series.

Abstract:

Over a billion people in sub-Saharan Africa Asia andthe Americas are infected with one or more helminthspecies causing morbidity that helps maintain the viciouscycle of poverty decreased productivity and inadequatesocioeconomic development. This report presents an evaluation of current research andchallenges in controlling the helminthiases of public healthimportance including onchocerciasis lymphatic filariasis soil-transmitted helminthiases schistosomiasis food-bornetrematodiases and taeniasis/cysticercosis. The evaluationcovers five major themes - intervention epidemiology andsurveillance e.

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