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Respiratory genetics

Author: Edwin K Silverman
Publisher: London : Hodder Arnold ; New York : Distributed in the United States of America by Oxford University Press, ©2005.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection, bioinformatics, and functional  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Respiratory genetics.
London : Hodder Arnold ; New York : Distributed in the United States of America by Oxford University Press, 2005
(DLC) 2006275793
(OCoLC)62176824
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Edwin K Silverman
ISBN: 9781444114669 1444114662
OCLC Number: 650076086
Description: 1 online resource (xix, 527 pages) : illustrations (some color)
Contents: pt. 1. Key concepts in respiratory genetics --
Overview of human genetics / Edwin K. Silverman and Scott T. Weiss --
Phenotypes for human respiratory genetics / Augusto A. Litonjua and Scott T. Weiss --
Testing for association in genetics studies / Nan Laird, Peter Kraft, Christoph Lange, and Kristel Van Steen --
Molecular characterization of genetic variation --
Sample collection and processing in human respiratory genetics / Benjamin A. Raby, Jody S. Sylvia, and Edwin K. Silverman --
Genetic variation, genotyping, and sequencing / Benjamin A. Raby, Jody S. Sylvia, and Edwin K. Silverman --
Bioinformatics --
Public databases and SNPs / Ross Lazarus --
Genomics and proteomics in lung disease: microarrays and bioinformatics issues / Isaac S. Kohane --
Functional genomics --
Clinical functional genomics / David J. Halsall and Elizabeth A. Davidson --
Expression and purification of recombinant proteins / Damian C. Crowther --
Functional characterization of protein / Didier Belorgey and David A. Lomas --
Biophysical analysis of proteins and protein-protein interactions / Timothy R. Dafforn --
Crystallography, nuclear magnetic resonance, and modeling / Roger B. Dodd and Randy J. Read --
Functional analysis of mutant proteins in cells / Paul D. Upton and Nicholas W. Morrell --
Genomic physiology in animals / Steven D. Shapiro and Dawn L. DeMeo --
Pharmacogenetics / Kelan G. Tantisira and Jeffrey M. Drazen --
pt. 2. Obstructive lung diseases --
Asthma genetics / Juan C. Celedon, Benjamin A. Raby and Scott Weiss --
Chronic obstructive pulmonary disease / Craig P. Hersh, Dawn L. DeMeo, and Edwin K. Silverman --
Cystic fibrosis / Joshua Groman and Garry R. Cutting --
pt. 3. Interstitial lung diseases --
Idiopathic pulmonary fibrosis / Karl W. Thomas and Gary W. Hunninghake --
Sarcoidosis / Paul A. Beirne, Stavros E. Anevlavis, and Roland M. du Bois --
pt. 4. Miscellaneous pulmonary conditions --
Pulmonary hypertension / James E. Loyd, John H. Newman, and John A. Phillips III --
Genetics of lung cancer / Rebecca Suk and David C. Christiani --
Respiratory infections / Michael F. Murray and Peter V. Tishler --
Congenital, metabolic, and neuromuscular diseases / Natasha Y. Frank and Peter V. Tishler --
Other rare lung diseases --
Disorders of surfactant homeostasis / Ralph J. Panos and Bruce C. Trapnell --
Lymphangioleiomyomatosis / Francis X. McCormack --
Hermansky-pudlak syndrome / Lisa R. Young and Francis X. McCormack.
Responsibility: edited by Edwin K. Silverman [and others].
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Abstract:

There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume. The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection, bioinformatics, and functional genomics. This is followed by a series of disease-specific chapters that review epidemiology, natural history, monogenic determinants, complex disease components, disease management, and l.

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"(An) excellent introduction to the topic of respiratory genetics for people moving into the field but the book will also be a valuable reference source for investigators who already have a working Read more...

 
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