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A review of selected literature (1995-2009) on the carcinogenicity of trichloroethylene (TCE)

Author: Pete Watts; Dick Heederik; G B G J (Frits) van Rooy; IRSST (Québec)
Publisher: Montréal, Qué. : Institut de recherche Robert-Sauvé en santé et en sécurité du travail, 2010
Series: Studies and research projects (IRSST (Québec))., Report ;, R-653.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
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Genre/Form: Electronic books
Additional Physical Format: Print version
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Pete Watts; Dick Heederik; G B G J (Frits) van Rooy; IRSST (Québec)
ISBN: 9782896314737 2896314733
OCLC Number: 685237043
Description: 1 online resource (vi, 82 pages).
Contents: 1 Introduction --
2 Recap of issue, existing knowledge and research objectives --
3 Methods --
Recent (1995-2009) cancer literature --
Earlier (pre-1995) cancer literature --
Rodent tumours: mode-of-action and relevance to humans --
4 Results --
Cancer epidemiology overview (up to 1995) --
Cancer epidemiology (1995-2009) --
General --
Exposure evaluated by biological monitoring --
Exposure evaluated by job exposure matrices --
Exposure evaluated by job histories --
Laboratory animal cancer overview (up to 1995) --
IARC overview --
Oral studies: mouse --
Oral studies: rat --
Inhalation studies: mouse --
Inhalation studies: rat --
Inhalation studies: hamster --
Dermal studies: mouse --
Laboratory animal cancer data (1995-2009) --
Modes-of-action for TCE tumours in laboratory animals: an overview --
General comments --
TCE, rodent tumours and Mode-of-Action --
TCE and generation of tumours as a function of exposure route --
5 Discussion (including scope and limits of results) --
TCE carcinogenicity: overview of laboratory animal studies --
TCE carcinogenicity: overview of epidemiology studies --
TCE exposure route and cancer target tissues --
Effect of duration and latency period on cancer risk --
6 Conclusion --
TCE and cancer in laboratory animals --
TCE and cancer in humans --
TCE exposure route and cancer target tissues.
Series Title: Studies and research projects (IRSST (Québec))., Report ;, R-653.
Other Titles: Chemical substances and biological agents
Revue sélective de la littérature (1995 à 2009) sur la cancérogénicité du trichloroéthylène (TCE)
Responsibility: Pete Watts, Dick Heederik and G.B.G.J. (Frits) van Rooy.
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